Thought Leadership | Today's Clinical Lab

The future of STI diagnostics lies in combining molecular accuracy with operational simplicity.

Why STI Testing Still Isn’t Decentralized—Rethinking STI Diagnostics from Sample to Result

Siew Veena Sahi, MD

Bridging the diagnostic gap means tackling preanalytical challenges and designing workflows that go beyond instrument-centric approaches

Quagliata sat down with Today’s Clinical Lab at the Association for Molecular Pathology’s annual meeting in November.

Molecular Pathology Will Lean Further into Liquid Biopsy and Proteomics in 2026

Scott Wallask, BA, Luca Quagliata, PhD, BCMAS, COA

Thermo Fisher’s Luca Quagliata also discusses pathologists’ desire for rapid turnaround times

Clinical labs are uniquely positioned to bring emerging scientific discoveries to the forefront, enhancing patient care.

How Clinical Lab Operations Are Evolving for 2026 and Beyond

Misty Phillips, MLS(ASCP)MB, Ellie Mahjubi, MSTM, MBA, Noreen Hong, MBA, Richard Knight, MD, Jane Li

Five experts at Thermo Fisher Scientific share their perspectives on technology, workforce, and operational shifts shaping the future of the clinical lab

Instead of relying solely on clinical endpoints over extended treatment periods, the research examined whether molecular signals could reveal pharmacodynamic activity within the first few days of treatment.

Rapid Transcriptomics Brings Actionable Data to Early-Phase Topical Trials

Stéphanie Légaré, PhD

Early transcriptomic readouts reveal pharmacodynamic activity in skin within days—a shift toward earlier molecular decision-making

If even 1 percent of adults in the US became kidney or partial liver living donors, the waitlists for kidney and liver transplants would significantly decrease.

Enhancing Transplant Success with Living Organ Donation and Advanced Diagnostics

Tina Liedtky

As demand for organs grows, laboratory diagnostics remain central to donor evaluation and transplant success

About 800,000 people have a heart attack every year in the US alone.

Can Better Diagnostics Lead to Improved Treatment for Cardiovascular Diseases?

Simon Williams, MBBS

From biomarkers to imaging, new lab-based diagnostics are transforming how cardiovascular risk is detected and managed

Researchers are now targeting clonal hematopoiesis and building new solutions to help make liquid biopsy a frontline defense in the fight against cancer.

Beyond the Blood Draw: Making Liquid Biopsy More Accurate, One Mutation at a Time

Matthew Oberley, MD, PhD

As liquid biopsy becomes a standard tool in oncology, distinguishing tumor signals from clonal hematopoiesis is essential for accurate results

Among acute myeloid leukemia (AML) subtypes, acute promyelocytic leukemia (APL) is both clinically urgent and therapeutically promising.

Streamlining Acute Promyelocytic Leukemia Diagnosis: The Case for a Unified PML-RARA Testing Solution

Meghana Malur, PhD

Detecting all PML-RARA fusion isoforms in a single assay could help simplify the diagnostic workflow for acute promyelocytic leukemia

The natural answer to this conundrum is to reimagine the blood testing journey around the needs and preferences of the patient.

9 Metrics to Guide a Patient-Centric Blood Testing Process

Kimberly Wilson

How labs can assess performance, enhance patient engagement, and build trust through a patient-focused approach to blood testing

Addressing the complex biology of progression is a major challenge in managing MS patients.

Capturing the Elusive: Why Multi-Protein Biomarkers Tests Are the Future of Measuring MS Progression

Ferhan Qureshi

Exploring how precision biomarkers can reveal hidden disease dynamics and drive a new standard of MS care

Having effective conservation strategies, like patient blood management, always helps stabilize and improve patient care.

Why Blood Management Is Especially Important During Times of Anticipated High Trauma

Sherri Ozawa, MSN, RN

Innovative diagnostics and patient blood management strategies are redefining how hospitals respond to seasonal blood shortages

Blood banks are critical for processing and storing blood and blood components.

Where Sustainability Meets Security: Improving Blood Banking Cold Storage Equipment

Lyndsay Mountz

Blood banks are increasingly seeking more sustainable options that can still meet regulatory requirements

Scientist examining a blood sample in a laboratory focused on sample management processes

Transforming Sample Management to Advance Better Science

Sapio Sciences

How modern labs are improving efficiency, ensuring traceability, and strengthening trust in their data

NGS-based assays are now considered standard for optimal treatment planning in many tumor types.

Rapid In-House NGS Is Closing the Gap in Precision Cancer Therapy

Luca Quagliata, PhD, BCMAS, COA

Automated NGS reduces complexity and cost, enabling community hospitals to expand testing without major infrastructure investments

Currently, LDTs can be created and implemented in a matter of weeks or months.

Why Clinical Labs Must Still Lead on Laboratory-Developed Test Quality

Shawn Hood

Oversight of the laboratory testing field must balance safety with speed and innovation