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cfDNA continues to gain momentum as a transformative tool in laboratory medicine.
|2 min read

Beyond Prenatal Testing: Cell-Free DNA Expands into Transfusion and Transplant Medicine

A new CAP article highlights the growing clinical utility of cfDNA across diagnostic and monitoring applications
byMiriam Bergeret, MSc
For clinical laboratories, the development reflects a broader shift in respiratory testing toward decentralized models.
|2 min read

QuidelOrtho Acquires LEX Diagnostics, Expands Ultra-Fast PCR Platform

QuidelOrtho has acquired LEX Diagnostics, adding a CLIA-waived multiplex RT-PCR system delivering respiratory results in less than 10 minutes
byToday's Clinical Lab
Fentanyl remains a leading driver of drug overdose deaths in the US, yet detection in clinical practice remains inconsistent.
|2 min read

Labcorp Launches FDA-Cleared 10-Minute Rapid Fentanyl Urine Test

New point-of-care test detects fentanyl metabolite norfentanyl, extending detection up to 48 hours to support faster clinical decisions in acute care settings
byToday's Clinical Lab
While PCR remains the dominant method in clinical molecular diagnostics, demand continues to grow for faster and more flexible workflows that can reduce time to result and expand testing outside centralized laboratories.
|1 min read

Engineered PCR and Isothermal Enzymes Aim to Accelerate Molecular Diagnostics Workflows

Watchmaker Genomics launches new PCR and RPA enzyme systems designed to improve speed and performance in molecular diagnostics
byToday's Clinical Lab
The collaboration also reflects growing interest in ctDNA-based assays as tools for more precise disease monitoring and personalized treatment strategies.
|2 min read

Quest Expands Haystack MRD ctDNA Testing in City of Hope Cancer Trials

A multi-site study will evaluate how a ctDNA assay may support residual disease detection and treatment monitoring in solid tumors
byToday's Clinical Lab
A major focus of the latest update is a restructuring of head and neck cancer protocols.
|2 min read

CAP Updates Cancer Protocols, Clarifies MMR/MSI Testing Discordance in New Article

The updates underscore shifts toward more standardized cancer reporting and more integrated interpretation of MMR/MSI testing in clinical decision-making
byMiriam Bergeret, MSc
The simulation model examined HIV infections across 18 states, with populations representing different groups of age, race, and sex.
Updated |2 min read

Modeling Study Projects 10% Increase in HIV Incidence with Reductions in HIV Testing Funding

Researchers used a computer model to quantify the effect of funding cuts for HIV testing
byJohns Hopkins Medicine
The study stands out compared to similar research because the model’s results were validated across multiple independent datasets, according to the researchers.
|2 min read

New AI Model Can Detect Multiple Cognitive Brain Diseases from a Single Blood Sample

The model is built from one of the world’s largest neurodegenerative protein datasets
byLund University
The research was carried out by Carles López Mateu, María Gómez Mahiques, F. Javier Gil Terrón, Víctor Montosa i Micó, Juan M. García-Gómez and Elies Fuster García, in collaboration with researchers from Oslo University Hospital.
|2 min read

A New Biomarker Helps Assess the Aggressiveness of Glioblastoma

Developed by the ITACA BDSLab, it can identify different patterns of tumor growth and independently predict patient survival
byUniversitat Politècnica de València
For multi-cancer detection, the test achieved a high level of overall accuracy.
Updated |3 min read

Researchers Develop Low-Cost Blood Test to Detect Multiple Cancers from a Single Sample

The method analyzes genome-wide DNA methylation in blood to detect liver, lung, ovarian, and stomach cancers, as well as other diseases
byUniversity of California - Los Angeles
Filipe Lima, first author of the article: “The new test analyzes not just one, but three different classes of antibodies, which increases sensitivity and helps distinguish between exposure to the bacillus, active infection, and prior contact.”
|4 min read

Blood Test Using AI Paves the Way for Early Diagnosis of Leprosy

Researchers analyzed a molecule capable of identifying new cases of leprosy before the onset of more severe lesions
byFundação de Amparo
The findings suggest that leveraging IntelliSep to enable early sepsis detection can drive repeatable patient-centered outcomes in diverse ED settings.
|2 min read

Multicenter Study of IntelliSep Shows 19% Reduction in Sepsis Mortality

The findings report double-digit operational improvements across four hospitals
byCytovale
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