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The Lednev lab uses a laser technique called Raman spectroscopy to analyze the chemical composition of materials.

Researchers Develop New Laser Technique to Test mRNA-Based Therapeutics

University at Albany

Deep-UV Raman technology enables precise mRNA measurement with minimal lipid interference

Most cell-free DNA tests aim to detect tumors by sniffing out changes in cell-free DNA that accompany malignant transformation.

Noninvasive ‘Fragmentome’ Test Expands Liquid Biopsy to Liver Cirrhosis and Other Conditions

American Association for the Advancement of Science (AAAS)

The assay builds on the clinical potential of liquid biopsy platforms and could expand this technology’s utility to detect conditions besides cancer

Pooja Ghatalia, MD, an Associate Professor in the Department of Hematology/Oncology at Fox Chase Cancer Center.

Blood Test Predicts Which Bladder Cancer Patients May Safely Skip Surgery

Temple University Health System

Positive results from the RETAIN-2 trial demonstrate that a response-adapted bladder-preservation approach involving neoadjuvant chemoimmunotherapy can be considered in select patients

The reference material will help crime laboratories accurately analyze genetic evidence that has degraded or contains DNA from multiple individuals.

NIST Releases New Forensic Genetic Reference Material to Help Crime Laboratories Analyze Challenging Cases

National Institute of Standards and Technology

DNA laboratories can use the samples to help train analysts and validate forensic tests

These tools could strengthen clinical trial planning and, with further refinement, inform early care decisions.

Study Shows Blood Test Can Predict Onset of Alzheimer’s Symptoms Years in Advance

Foundation for the National Institutes of Health

FNIH Biomarkers Consortium “clock model” can use a single blood test to estimate the onset of symptoms within three to four years

COVID-19 Vaccination During Pregnancy May Help Prevent Preeclampsia

Ann & Robert H. Lurie Children's Hospital of Chicago

The findings offer unprecedented insight into preeclampsia prevention, independent of the direct effects of COVID-19 infection.

Tumors are composed of different cancer cells that vary in their aggressiveness and sensitivity to treatments, and further research is needed to understand how liquid biopsies can capture this diversity.

DNA Barcoding Reveals the Complexity of Breast Cancer Liquid Biopsies

Olivia Newton-John Cancer Research Institute

Optimized DNA barcoding showed that similar-looking tumors can release different amounts of DNA into the bloodstream

Under the redlining policy, federal agencies and banks created maps that designated neighborhoods as A (“best”) to D (“hazardous,” colored red on maps) for mortgage lending based on race, ethnicity, and class.

Have Associations Between Historical Redlining and Breast Cancer Survival Changed Over Time?

Wiley

Study finds that disparities generally narrowed from 1995–2014, but subsequently widened

One of the most widely recognized issues is that AI models can replicate societal biases and systematically underestimate risk or misclassify disease in historically marginalized populations.

ADLM Advocates for the Federal Government to Support Equitable Healthcare AI

Association for Diagnostics and Laboratory Medicine

The statement calls on Congress and federal agencies to modernize existing laboratory regulations and to implement policies to ensure that AI clinical systems are safe and effective

The researchers used retrospective clinical data from 113 patients treated for prostate cancer at University of California Los Angeles (UCLA) Jonsson Comprehensive Cancer Center.

New Study Unlocks Important Information About How to Treat Recurring Prostate Cancer

National Comprehensive Cancer Network

Routine PSMA PET/CT scans could help doctors select the best treatments for long-term outcomes in patients with recurring prostate cancer after surgical removal of the prostate

Cancer cells (red) stick to mesothelial cells (green) and form hybrid spheres that cut into surrounding abdominal tissue.

Why Ovarian Cancer Spreads So Rapidly in the Abdomen

Nagoya City University

Study finds floating ovarian cancer cells recruit mesothelial cells in abdominal fluid to create cancer clusters

The 2026 Lab Manager Leadership Summit takes place April 20-22 at the Gila River Resorts & Casinos–Wild Horse Pass, located just south of Phoenix.

2026 Lab Manager Leadership Summit Will Bring Clinical Laboratory Expertise and Networking

Scott Wallask, BA

Medical lab speakers to explore career positioning, communication techniques, and operation scaling

After leaving the Gerdt Lab for a post-doctoral position at the Swiss Federal Technology Institute of Lausanne, Zhiyu Zang decided to focus on the human immune system.

Researchers Find Chemical Solution for Tackling Antibiotic Resistance

Indiana University

The discovery could be used to help manage with hard-to-treat bacterial infections in humans

Across all vaccination ages and vaccine types, less frequent screening was consistently preferred.

Study Suggests Far Fewer Cervical Cancer Screenings Are Needed for HPV-Vaccinated Women

American College of Physicians

The findings suggest existing screening guidelines may be overly sensitive for women vaccinated at younger ages

This technology supports minimally invasive cancer detection using a simple blood draw and a fully automated workflow.

A New ‘Lab-on-a-Disc’ Device Paves the Way for More Automated Liquid Biopsies

Mass General Brigham

High-throughput, automated EV processing from small blood samples could streamline multiplexed liquid biopsy workflows in clinical labs

While histologic examination and immunohistochemistry remain the foundation of cancer diagnosis, the authors explain that molecular profiling can provide critical additional insight when conventional approaches fall short.

CAP Highlights Molecular Testing to Clarify Difficult-to-Classify Tumors

College of American Pathologists

CAP authors outline how genomic, transcriptomic, and epigenetic profiling can support pathologists when conventional histology and immunohistochemistry fall short, particularly in cancers of unknown primary

BioPathNet is an AI method for analyzing such biomedical knowledge graphs.

New AI Method Analyzes Biomedical Knowledge Graphs to Reveal Diagnostic Targets

Helmholtz Zentrum München

The BioPathNet platform scans biomedical data networks to generate testable hypotheses that could support biomarker discovery and diagnostic development

Reduction in depression diagnoses since the start of the COVID-19 pandemic, and failure to recover to expected rates of diagnoses following the pandemic.

Diagnoses of Major Conditions Failing to Recover Since the Pandemic

King's College London

There has been a lasting and disproportionate impact of the COVID-19 pandemic on diagnosis rates for conditions including depression, asthma, and osteoporosis

Across the globe, measles activity remains elevated.

US Risks Losing Measles Elimination Status as Cases Continue to Rise, Experts Warn

Global Virus Network

Global Virus Network urges measles-mumps-rubella (MMR) vaccination for unvaccinated children and adults to prevent avoidable illness and death

Type 2 diabetes (T2D) is a growing health concern in sub-Saharan Africa, but it is often underdiagnosed or misdiagnosed.

Mapping Proteins in African Genomes Reveals New Paths to Fight Type 2 Diabetes

Helmholtz Zentrum München

The research could help develop representative biomarkers and treatment strategies—bringing more precise and effective health care to millions of people