Gene Expression

|2 min read

Epigenetic Combo Therapy Shows Promise Against Rare Sarcomas

The team’s next step is to introduce immunotherapy to treat soft tissue sarcomas
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First Two Children Receive New Gene Therapy for Rett Syndrome

Phase 1/2 trial showed the safety and therapeutic potential of administering a novel transgene

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E. coli-Produced HPV Vaccine Proves to Be Safe in Phase 2 Trial

The recombinant 9-valent HPV vaccine was well tolerated by all participants and caused no serious adverse effects
|3 min read

Rare Musculoskeletal Condition Treatment Shows Promise in Phase 2 Trial

Drug candidate indirectly blocks mutant ACVR1 gene activation and prevents formation of new bone lesions
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Multiomic Analyses Identify New Pneumonia Biomarkers

Some nine sets of metagenomic and transcriptomic biomarkers outperformed existing clinical prediction models
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New Study Reveals Why Kidney Cancers Become Metastatic

Novel renal cell carcinoma model may help predict whether tumors have genomic potential to become aggressive
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Location May Influence Tumor Cell’s Identity and Role in Cancer Biology

New approach could provide insights into cancer progression, treatment response, and precise therapies
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New AI RNA Sequencing Tool May Simplify Gene Discovery

The long-read sequencing tool accurately identifies and quantifies new, relevant transcripts in any genome
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Transposable Elements Causing Rare MSL3 Syndrome Identified

Mutations in the MSL3 gene can lead to a global delay in the development of multiple organs in children
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Large-Scale Study Links microRNAs in Pancreatic Cells to Diabetes

Genetic analysis shows how miRNAs control gene expression in pancreatic islets
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New Approach Successfully Traces Genomic Variants Back to Genetic Disorders

Study shows genotype-first approach uncovers new links to genetic conditions
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Structure and Function of Newly Discovered CRISPR Immune System

In tandem papers in Nature, researchers report effects of Cas12a2
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