Drug Therapy

|2 min read

New Drug Slows Rare, Debilitating Genetic Disease in Trials

The NIH-supported clinical trial could lead to the first effective treatment for ACDC disease
Updated |2 min read

PARP Inhibitor Delays Uterine Cancer Recurrence in Phase 2 Trial

There are currently no approved maintenance therapies for metastatic and recurrent uterine/endometrial cancer
|2 min read

mAb Combo Therapy Safe to Treat Advanced Cancers

CS1002 plus CS1003 showed promising antitumor activity and had a manageable safety profile across a broad dosing range in trials
|2 min read

Arginine Starvation Abates Rare Lung Cancer

The treatment significantly increases the survival of people with malignant mesothelioma, according to results from Phase 3 trial
|2 min read

mAb–Drug Therapy Combo Improves NSC Lung Cancer

Phase 2 trial finds durvalumab–ceralasertib boosted immune response and improved outcomes in patients with lung cancer
|1 min read

Androgen Receptor Modulator Drug Could Improve Breast Cancer

Phase 2 trial results indicate benefits of the new way of treating advanced ER+ breast cancer
|2 min read

Combination Hormone Therapy May Delay Cancer Progression

Prostate cancer affects 1 in 8 men and causes 34,000 deaths each year in the US
|3 min read

Comprehensive Analysis Reveals 370 Novel Anticancer Drug Targets

Second generation of the Cancer Dependency Map uncovers priority drug targets with strong links to specific cancer types
|2 min read

Genetic Priority Score Finetunes Drug Development

Innovative approach integrates genetic data to identify drug targets with high potential for clinical trial success

|2 min read

Bendamustine Treatment before CAR T-Cell Therapy May Be Detrimental

CAR T-cell therapy recipients with refractory lymphoma showed poorer treatment outcomes when treated with bendamustine

|3 min read

New Test Drug–Empagliflozin Combo Abates CKD Side Effects

Some 70 percent of patients who received the test drug with a standard-care drug experienced a significant drop in albuminuria
|2 min read

The Impact of Suboptimal Cancer Drug Trials on Patient Health

 About 60 of 400 Phase 2 and 3 cancer drug trials registered between 2016 and 2017 had suboptimal control arms
Page 1 of 4