Identifying Gene–Disease Relationships in the Clinical Exome
Genomenon Inc.
The six-month study combined computational indexing of 9.5 million full-text genomic publications with a systematic literature review
Computation
New Prediction Model Aids in Early Detection of Preeclampsia
Swathi Kodaikal, MSc
The model analyzes methylation changes in the cell-free DNA of pregnant women at risk of preeclampsia
Fine-Tuning Single-Cell Tumor Profiling to Predict Cancer Outcomes
Swathi Kodaikal, MSc
Newly developed computational tool accurately identifies, characterizes, and differentiates cell types in tumor samples
What’s New in Histology?
Michael Schubert, PhD
Recent news from the world of tissue-based diagnostics
Proteogenomics Drives Novel Ovarian Cancer Diagnostic Approach
Fred Hutchinson Cancer Research Center
A 64-protein pattern could identify which patients would or wouldn’t benefit from standard ovarian cancer treatments
Genomic Medicine Milestones: The Resurgence of CRISPR Gene Editing
Rachel Diamant, MSc
The future of genomic medicine relies on technical considerations and ongoing industry collaboration
New Clinical Tool Predicts Cancer Risk in Patients with Clonal Hematopoiesis
Dana-Farber Cancer Institute
Findings may drive clinical trials for potential treatment options for CH patients with high blood cancer risk
New Computational Tool Characterizes Progenitor Cells in AML Patients
Center for Genomic Regulation
Findings may help reduce rates of relapse and improve the prognosis and successful treatment of acute myeloid lymphoma
Overcoming Challenges for Predicting Interactions between Cancerous Cells and Red Blood Cells
Amanda Randles, PhD
Robust sampling strategies and suitable metrics may improve accuracy
AI Is Broadening the Impact of Clinical Informatics
Jake Moskowitz, DVM, PhD
Advancing AI pathology and multi-omics data integration will expand the role of clinical informatics in health care