NIH’s ComboMATCH to Test New Drug Combinations Guided by Tumor Biology
National Institutes of Health
ComboMATCH comprises several Phase 2 treatment trials that will each evaluate a drug combination plus a chemotherapy drug
Precision Medicine
Identify All Relevant Pathogens with Just One Workflow and Easy Analysis
Zahraa Chorghay, PhD
Precision metagenomics offers an efficient and comprehensive approach for characterizing the microbial environment
Embracing Data-Driven Preclinical Drug Development
Kristen Eisenhauer, BS, EMBA
Having near real-time access to data boosts the efficiency of the drug development process
Delivering on the Promise of Personalized Breast Cancer Therapy
Baylor College of Medicine
Identifying the right set of patients using a molecular test can help effectively deliver a personalized, chemotherapy-free treatment regimen
FDA Takes Additional Steps to Advance Decentralized Clinical Trials
U.S. Food and Drug Administration
Decentralizing clinical trials may improve accessibility, participant diversity
Genetic Mutations Linked to Temporal Lobe Epilepsy Identified
Mass General Brigham
Findings point to the potential for using existing cancer therapies to treat drug-resistant epilepsy
Next-Generation Tools Bring Precision Medicine to the Clinic
Thomas Ybert, PhD
Precision medicine is evolving rapidly, but knowledge gaps remain
New Clues to Origins of Wilms Tumor in Children Uncovered
Children’s Hospital Los Angeles
Findings could improve the diagnosis and treatment of a rare kidney cancer with high pediatric prevalence
Brain Networks Involved in Epileptic Seizures Identified
University College London
Surgically disconnecting specific networks in the brain may help patients live epilepsy-free for a longer time
Benefits of Digitized Pathology for Clinical Trial Sponsors and Pathology Teams
Monika Lamba, MD, PhD
Can advances in tech-enabled solutions and workflows optimize diagnostic analysis while reducing the burden on pathologists?
Key Mechanisms of NK Cell Dysfunction Revealed
university of science and technology of china
Study explains how tumors evade natural killer cells’ response from a membrane topology perspective, offers new immunotherapy strategies
AACR Applauds, Backs NCI’s National Cancer Plan
American Association for Cancer Research
Comprehensive plan provides an updated roadmap and strategies to end cancer as we know it
Breath Analysis Tech To Help Monitor Gut Health, Microbiome
Owlstone Medical
Collected data can be used to develop personalized health plans for those with digestive health issues
New Immunotherapy Delivery Option for Leptomeningeal Disease in Cancer Patients
University of Texas MD Anderson Cancer Center
Concurrent intrathecal and intravenous treatment is safe and improves outcomes in a subset of patients with melanoma
Meta-analysis: Vaginal Swabs Are Most Reliable for STI Detection
American Academy of Family Physicians
Relying on urine testing alone may result in about 400,000 undetected cases a year, per new analysis
FDA Issues Guidance to Support Accelerated Approval of Oncology Clinical Trials
U.S. Food and Drug Administration
Guidance discusses ways to improve clinical trial design and data analysis to reduce uncertainty for cancer patients
Experts Recommend Genetic Testing to Prevent Fatal Brain Infection
Emerald Lake Safety
MS and PML experts argue that preventive screening should become the new standard of care
Key Source of Loss of CAR T Cell Potency Identified
Dana-Farber Cancer Institute
Discovery may help design drugs that prevent T-cell therapies from losing their efficacy over time
Overcoming Challenges for Predicting Interactions between Cancerous Cells and Red Blood Cells
Amanda Randles, PhD
Robust sampling strategies and suitable metrics may improve accuracy
Decentralizing HCV Diagnosis for Vulnerable Populations
Germans Trias i Pujol Research Institute (IGTP)
Dried blood spot samples effectively assess cure and differentiate reinfection after HCV treatment