Precision Medicine Articles | Today's Clinical Lab

A T cell attacks a cancer cell by binding to specific receptors on the cell surface.

Protein “Barcodes” Can Precisely Guide CAR T Cells to Targets

Children's Hospital of Philadelphia

Identifying peptide backbones that link protein complexes to cancer cells can help maximize CAR therapy applicability to different tumor types

A female clinician wears virtual reality goggles and touches a virtual screen with icons and digital code.

How Does AI Augment Predictive Cancer Research and Diagnosis?

Mateusz Tylicki, BSc

Deep learning and AI-based decisions are becoming increasingly reliable but remain far from being adapted to cancer diagnostics

Vector illustration of a female researcher with a headscarf adjusting a microscope in a laboratory and discussing with other scientists on a video call.

New Digital Pathology Network to Empower Experts, Labs, and Patients

Paige AI

Pathologists can share images and consult a network of experts to deliver timely, cost-effective patient care

Human body organs, lungs, heart, liver, kidneys, and brain, in small white trays isolated on a gray background.

Gene Therapy to Treat Rare and Hereditary Diseases

Norwegian University of Science And Technology

Researchers are finding clues that may help treat rare and deadly diseases using mini-organs and advanced technology

Noninvasive Fetal Screening Effectively Detects Abnormalities

Massachusetts General Hospital

Noninvasive method has the potential to survey the entire fetal exome without the need for amniocentesis

A white cyborg robotic hand pointing a finger to a human hand with a stretched finger against a background with circuits and "AI" written.

Humans Beat AI in Making Personalized Medicine Decisions

Charité – Universitätsmedizin Berlin

The study highlights the limits of large language models in precision oncology and the scope for improvement

A futuristic drug capsule on a circuit indicating the use of AI in drug development.

AI’s Impact on Drug Development: Opportunities for Pharmaceutical Leaders

Claire Aldridge, PhD

Explore the transformative impact of artificial intelligence on drug development and its role in the future of pharmaceutical innovation

3D rendering of a quaternary structure of protein molecule.

Identifying Protein Biomarkers to Advance Precision Medicine

Thomas Moehring, PhD, Stephanie Samra, MSc

Proteome analysis using multiomic tools helps obtain a holistic and accurate patient health profile

A clinician holds a model of a human kidney showing the anatomy.

Novel Drug Improves Rare Kidney Disorder in Phase 3 Trial

University of Minnesota Medical School

Some 42 percent of patients treated with sparsentan showed reduced proteinuria

A man holding a cigarette before his chest where his lungs can be seen as an X-ray film showing a reddened affected area on the left.

ACS Updates Lung Cancer Screening Guideline

American Cancer Society

The Society aims to reduce lung cancer deaths with updated screening recommendations

3D rendering of the human skeleton and muscle anatomy of the body with a group of sore joints indicating inflammation.

FDA Approves Interchangeable Biosimilar for Multiple Inflammatory Diseases

U.S. Food and Drug Administration

Wezlana has similar safety and efficacy as its reference product and is a cost-effective alternative for chronic inflammation

Graphic representation of bands of DNA sequence on a gel.

How Can Diverse Genomic Approaches Improve Rare Disease Research?

Tomi Pastinen, MD, PhD

Multiomic techniques can robustly screen and identify often-missed genetic determinants of rare diseases

Pills fallen out of a prescription drug bottle on a blue background.

Encaleret Restores Parathyroid Function in ADH1 Trial

Swathi Kodaikal, MSc

Some 3.9 in 100,000 people in the US are affected by ADH1, a major cause of nonsurgical hypoparathyroidism

The male clinician looks at spots and moles on a patient's back through a magnifying glass.

Neoadjuvant Shows Positive Response in Advanced Melanoma Trial

SWOG Cancer Research Network

Single-agent immunotherapy shrinks over half of advanced melanomas when given before surgery

X-ray of the lungs of a person with highlighted cancer in the left lung.

Perioperative Immunotherapy Significantly Improves NSCLC Outcomes

University of Texas MD Anderson Cancer Center

Results showed a 32 percent lower chance of cancer recurrence, progression, or death with immunotherapy plus chemotherapy versus chemotherapy alone

3D illustration of T cells attacking a cancer cell.

CAR T-Cell Therapy Shows Race-Agnostic Response in MM Patients

American Society of Hematology

Multiple myeloma patients treated with CAR T-cell therapy showed similar survival outcomes regardless of race or ethnicity

New Transfusion Guidelines Recommend Assessing Patient Comorbidities

Rutgers University

The expert panel developed recommendations to conserve blood supply and prevent transfusion-related illnesses

3D rendering of cancer detection or screening as a treatment for malignant cells with a biopsy or testing as an immunotherapy symbol.

VIGex Could Guide Patient Selection for Personalized Immunotherapy

Vall d'Hebron Institute of Oncology

Prediction tool classifies solid tumors based on inflammation status, thereby triaging cases that will benefit the most

Vector illustration of a female scientist works on the computer in the laboratory with a microscope and beaker icon, equipment, and test tubes on the desk.

Single-Arm Trials May Not Be Effective in Drug Development

German Institute for Quality and Efficiency in Health Care (IQWiG)

Experts urge EMA to prioritize evidence-based drug development over accelerated marketing authorization

FISH membrane stained image of mouse pancreas section.

Leveraging Next-Gen IHC Tools to Advance Precision Oncology Research

Swathi Kodaikal, MSc

Harnessing the power of multiplexing and RNA–protein studies could help design targeted cancer treatments