Content by PLOS

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New Monthly Pill Shows Potential as Pre-Exposure Prophylaxis HIV Drug Candidate

The compound, MK-8527, belongs to a novel class of antiretrovirals
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Study Tracks Physical and Cognitive Impairments Associated with Long COVID

Researchers following nearly 1,000 people with post-COVID-19 syndrome found few changes to their symptoms in the second year of illness
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The Impact of Suboptimal Cancer Drug Trials on Patient Health

 About 60 of 400 Phase 2 and 3 cancer drug trials registered between 2016 and 2017 had suboptimal control arms
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Ancient Viral Remnants in the Human Genome Are Active in Normal Tissues

Presence of endogenous retrovirus RNA in non-diseased tissues could affect use as a cancer biomarker
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New Antibiotic Resistance Genes Identified in Tuberculosis

Analyzing the genetic sequences and antibiotic susceptibility of more than 10,000 global M. tuberculosis isolates
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Mutations in SARS-CoV-2 Receptor-Binding Domains May Result in Variants

A recent literature review helped researchers map out the spike protein mutations that resist antibody binding
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Human Microbiome Research Excludes Developing World

Microbiome research is heavily biased in favor of wealthy countries such as US and UK
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COVID-19 Variants with Potential to Escape Cellular Immune Response

New study identifies mutations that may be worth deeper surveillance
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CDC Internal Investigation Probes First Batch of COVID-19 Tests

False positive reactivity in earliest RT-PCR tests due to contamination and design errors
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Massive Study Reveals Editorial Bias and Nepotism in Biomedical Journals

Authors identify a subset of journals where a few authors were responsible for a disproportionate number of publications
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Genetic Study of Heart Defects and Autism Finds New Causative Genes

Almost two dozen genes that contribute to heart defects were identified
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Delaying Second Dose of COVID-19 Vaccines May Be an Effective Strategy

Study examines how to minimize new infections and hospitalizations with limited vaccine supply and distribution
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