Content by Children's Hospital of Philadelphia
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Researchers Develop Antioxidant Strategy to Address Mitochondrial Dysfunction Caused by SARS-CoV-2
Preclinical data suggests a new strategy for treating complex cases of COVID-19 independent of mutations and variants
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Protein “Barcodes” Can Precisely Guide CAR T Cells to Targets
Identifying peptide backbones that link protein complexes to cancer cells can help maximize CAR therapy applicability to different tumor types
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TEQUILA-seq Solves Long-Read RNA Sequencing Woes
Easy-to-implement technology reduces the per-reaction cost of target capture by two to three orders of magnitude as compared to commercial solutions
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More Accurate Computational Tool for Long-Read RNA Sequencing
The tool will allow for better diagnosis of rare genetic diseases caused by disrupted RNA
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The Use of Telemedicine in Child Neurology
Certain patients were more likely to use telemedicine even with the reopening of in-person appointments
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Researchers Develop Tool to Interpret Clinical Significance of Cancer Mutations
The software standardizes procedures to help researchers assess the impacts of over 13 million somatic cancer mutations
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Elevated Biomarker for Blood Vessel Damage Found in All Children With COVID-19
Researchers found elevated levels of the biomarker in children with SARS-CoV-2 infection, even if they had no symptoms
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Combining Genetic Information with EMRs to Pinpoint Childhood Epilepsies
Assessing clinical data across the lifespan identified the impact of genetic epilepsies on affected children's lives
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How the Gut Microbiome Develops in Early Life
CHOP researchers reveal critical new information on bacterial colonization of the infant gut
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Researchers Reveal Important Genetic Mechanism Behind Inflammatory Bowel Disease
The genetic mutation shares a link with the JAK2 pathway, an important target of multiple immunotherapies
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RNA Splicing in Clinically Accessible and Non-Accessible Tissues
Study reveals the true extent of what may be missed with current RNA sequencing methods
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