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Application Note

Optimize LC-MS Performance with Ultrapure Water Solutions

Discover how ultrapure water enhances sensitivity, traceability, and reliability in LC-MS for clinical laboratories

The accuracy of LC-MS (liquid chromatography-mass spectrometry) analyses directly impacts patient outcomes and lab efficiency. One factor in achieving high-quality results is the purity of water used throughout the workflow. Ultrapure water minimizes contamination, preventing ghost peaks and noisy baselines that can obscure critical data. By using ultrapure water, lab managers can ensure their instruments operate at peak sensitivity, allowing for the detection of even trace analytes in complex biological samples.

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Beyond improving sensitivity, ultrapure water offers traceability and consistency—two pillars of quality management in clinical settings. With advanced monitoring systems, labs can maintain high standards and meet regulatory requirements without worrying about water quality fluctuations. This means greater confidence in your data, fewer re-runs, and improved overall productivity. Investing in high-quality water solutions not only enhances the reliability of LC-MS results but also optimizes lab operations, helping your team focus on what matters most—delivering timely, accurate clinical insights.


Download MilliporeSigma's full guide of LC-MS water solutions to learn: 

  • How ultrapure water eliminates contamination risks in LC-MS workflows

  • Proven strategies for boosting sensitivity and reducing errors

  • Key tools for maintaining compliance and consistency in clinical analyses



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