FDA Announces Additional Steps to Modernize Clinical Trials
U.S. Food and Drug Administration
Digital health technologies could facilitate agile data collection and improve regulatory decision-making
Clinical Lab News
New Discoveries Highlight the Role of Tumor Vasculature in Metastasis and Immunotherapy
University of Virginia Health System
Targeting blood vessel proteins and preventing tumor cell invasion in lymph nodes may enhance cancer treatments’ efficacy and precision
New, Simple Blood Test to Diagnose De Vivo Disease
Institut Du Cerveau (Paris Brain Institute)
If used at an early stage, METAglut1 can accurately identify 80 percent of patients with Glut1 deficiency syndrome
“Micro Lungs” Could Accelerate the Study of Respiratory Diseases
The Rockefeller University
Mini-lung buds can be cultured and employed for high-throughput analysis of lung tissue infection without interfering variables
Genetic Correction of PSA Levels May Improve Prostate Cancer Detection Accuracy
University of California - San Francisco
Inherited genetic determinants can cause normal variations in PSA levels even in the absence of prostate cancer
NIH’s ComboMATCH to Test New Drug Combinations Guided by Tumor Biology
National Institutes of Health
ComboMATCH comprises several Phase 2 treatment trials that will each evaluate a drug combination plus a chemotherapy drug
AI Model Predicts Consequences of Gene Modifications
Gladstone Institutes
Researchers trained a computer model to understand the gene networks and how they go awry in disease conditions
Initiating r/r Lymphoma Treatment in Women: During vs. After Gestation
American Society of Hematology
Fighting relapsed/refractory lymphoma during pregnancy requires critical decision-making from patients and providers
Genetic Risks for SCAD Affecting Younger Women Revealed
University Hospitals of Leicester NHS Trust
First international genome-wide association meta-analysis identifies 16 genes that exacerbate SCAD risk
FDA Approves First Oral Antiviral Drug to Treat COVID-19 in Adults
U.S. Food and Drug Administration
Paxlovid reduced the proportion of people with COVID-19-related hospitalization or death by 86 percent
Key Proteins Driving Antibiotic Resistance in Bacteria Discovered
University of Tsukuba
ABCFs protect bacterial ribosomes, work in synergy with other proteins to convey antibiotic resistance
SWI/SNF Complexes “Bookmark” Cell Identity During Mitosis
St. Jude's Children's Research Hospital
Subunits of the SWI/SNF protein complex may play a key role in driving cancer development and differentiation
CRISPR-Cas9-Based Tool May Help Slow Antimicrobial Resistance Spread
University of Exeter
Researchers apply CRISPR-Cas9 editing to bacterial plasmids, exploit bacteria’s immune system
FDA Approves New Treatment for Pneumonia Caused by Acinetobacter Complex
U.S. Food and Drug Administration
The Acinetobacter species top the list of critical bacterial pathogens that pose the greatest threat to human health
“Molecular Triggers” Driving Breast Cancer Uncovered
Swathi Kodaikal, MSc
Complex patterns of mutations and hormonal fluctuations may have key effects on breast cancer etiology
HIV Declines among Young People, New Infections Drop
Centers for Disease Control and Prevention
Increased investments, innovation, and focus on equity are vitally needed to end the HIV epidemic
ImmunoCAP™ Test for Allergies Made More Accessible Across US
Thermo Fisher Scientific
Research-backed, low-cost testing supporting allergy diagnosis is now easily available to more people in more communities
Novel, High-Throughput Method for Screening Protein-Secreting Microbes
Tokyo Institute of Technology
Simple approach combines biosensors and microfluidics to screen large-scale libraries for industrially useful bacteria
Brain Processes Acute and Chronic Pain Differently: Early Studies
National Institutes of Health
Study shows preliminary results that could lead to new pain treatments and help improve quality of life in individuals
FDA Approves First Topical Gene Therapy for Dystrophic Epidermolysis Bullosa Wounds
U.S. Food and Drug Administration
Around 65 percent of the wounds treated with Vyjuvek showed complete wound closure in DEB patients