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New Method Allows Detecting Tumor by Measuring Its Temperature

Researchers have proposed a method for detecting cancer, other diseases by measuring the temperature inside the body

Russian Foundation for Basic Research

Russian Foundation for Basic Research (RFBR) was created by decree #426 of the President of the Russian Federation “On urgent measures for preserving scientific and technological potential of the Russian Federation” and is a self-governed state nonprofit organisation in the form of a federal organisation controlled by the Government of the Russian Federation. Being a representative of the state, the Foundation provides targeted diversified support to leading groups of scientists regardless of the organisation they represent. Support of initiative scientific research in all the principal directions of fundamental science is carried out strictly on a competition basis after a comprehensive evaluation.

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Published:Oct 25, 2021
|2 min read
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Cancers, blood flow disorders, arthritis, and other diseases alter body temperature, so one way to diagnose such diseases is to detect a temperature change. It is easy to do on the surface of the skin, for example with an infrared pyrometer. But it is impossible to accurately measure the temperature inside the body without damaging the skin with existing tools. A group of researchers with the participation of a RUDN University scientist proposed a radiothermography method that allows measuring the temperature distribution inside the body.

“The purpose of this study is to show the possibility of 3D visualization of the internal thermal field of a person using the results of measurements of radio brightness temperatures, simultaneously measured at different points of the body, using a multi-channel multi-frequency radiothermograph. The novelty of the approach considered is an attempt to more accurately localize the heat source position due to 3D visualization of the internal heat field of a body and monitoring the temperature dynamics of a heat point source inside the human body,” said Svetlana Agasieva, associate professor of the Department of Nanotechnology and Microsystem Technology at the Academy of Engineering of RUDN University.

Researchers have proposed a method, device, and software to accurately determine the location of the source of increased heat in the body. A small antenna is installed on the surface of the body, which can measure the internal temperature with an accuracy of one degree. The patient drinks an aqueous glucose solution, it is quickly absorbed into the blood and carried through the cells. Because of this, the body temperature rises evenly by one to two-tenths of a degree. However, if there is a malignant formation somewhere, the temperature in it will rise sharply by one or two degrees for a few minutes. This change can be detected by the device. To clarify the depth of the pathology location, the researchers developed a calculation method.

The device and the simulation results were tested experimentally with real patients. The method visualizes temperature "layers" on the screen of a computer. One can scroll through them with the mouse to accurately determine the depth of the heat source. Moreover, you can see on the video how the temperature changed in this area. In the future, the researchers will realize clinical trials of the device.

“The detailed information about the internal thermal field of a human body has made possible not only detection of an internal malignant tumor, but also the determination of the depth of its location. The new radiothermograph gives an opportunity for more detailed analysis of the state of the vascular system of the brain and early diagnosis of various brain pathologies. Of course, it is too early to talk about all the possibilities and advantages of the new radiothermograph, which will be confirmed during clinical tests that will begin in the near future,” said Agasieva.

- This press release was provided by the Russian Foundation for Basic Research