Today’s Clinical Lab-September-2025-Cover Image

VOLUME 27 - ISSUE 1 | September 2025COVER STORY

Pathogen Detection & Infectious Disease

Smarter Diagnostics, Reemerging Threats, and Lab-Driven Strategies

The Impact of Emerging Dolutegravir Resistance on Global HIV Treatment and Prevention

Dr. Obiageli Okafor discusses growing resistance to dolutegravir and the need for global access to affordable HIV treatment and prevention

byObiageli Okafor, MD, DrPH, MPH andThermo Fisher Scientific

Business

Transform System Strategies into Laboratory Action to Drive Long-Term Success

Strategies to improve revenue and customer satisfaction can be advanced through laboratory actions to build success and secure long-term goals

byTyler Radke, MLS(ASCP)CM

This year at ADLM, IVD manufacturers and software vendors expressed interest in fighting AMR with medical labs by raising more awareness with consumers about the risks involved.

Vendors and Clinicians Promote Fighting AMR Through Greater Public Awareness

Once again, clinical labs are at the forefront of a public health battle, this time against antimicrobial resistance

byScott Wallask, BA

Insight

Illustration of the measles virus particles with the word 'measles' in bold against an orange background.

Why Measles Is Spreading Again—And What It Means for Global Health

Measles is resurging in 2025 as falling vaccination rates and misinformation fuel a growing global health threat

byPallavi Upadhyay, PhD, CMPP

This “One Health” concept is driving cross-disciplinary efforts to address health challenges in humans, animals, plants, and ecosystems as a whole.

One Health in the Lab: Healthy Planet, Healthy People

One Health expert Oladele Ogunseitan explains how human, animal, and environmental health are linked, and what clinical labs can do to drive advances in all three

byMichael Schubert, PhD

Despite the alarming statistics, many sepsis-related deaths are preventable through rapid diagnosis and treatment.

Challenges and Advances in Sepsis Detection

FDA-approved tests like Intellisep and TriVerity™ demonstrate potential for early sepsis diagnosis

byZahraa Chorghay, PhD

Regulatory

The ACT label (accountability, consistency, and transparency), developed by the nonprofit organization My Green Lab, is a widely adopted and standardized ecolabel designed to visually communicate the environmental impact of laboratory products.

Greener Labs, Smarter Choices: What ACT Ecolabel 2.0 Means for Clinical Laboratories

Exploring the updated ACT Ecolabel 2.0 and helping lab managers drive sustainability across products, suppliers, and operations

byJordan Willis, BSc

Thought Leadership

Nucleic acid amplification testing (NAAT) methods frequently result in overdiagnosis, leading to unwarranted treatments and possible penalties for healthcare providers.

Improving C. difficile Diagnosis: Why Two-Step Algorithm Testing Makes a Difference

The two-step algorithm for C. diff improves diagnostic accuracy, reduces unnecessary treatments, supports antimicrobial stewardship, and helps avoid overdiagnosis-related penalties

byJimmy Lowery, MBA, MLS(ASCP)SBB

This gap leads to variability in care, delayed treatment, and wasted resources.

Bridging the Sepsis Diagnosis Gap: How Host Response Diagnostics Are Changing the Front Line

Sepsis remains elusive without a definitive test. A breakthrough in host response diagnostics may finally close the gap

byNathan A. Ledeboer, PhD

Technology

Emerging Technologies Guide: Fall 2025

Recent new and emerging technologies in the field of laboratory medicine from the 2025 September Pathogen Detection & Infectious Disease issue of Today's Clinical Lab

byToday's Clinical Lab