Immunology Articles | Today's Clinical Lab

T lymphocytes attached to a cancer cell artwork.

New Details on Idiopathic CD4 Lymphocytopenia Uncovered

National Institute of Allergy and Infectious Diseases

There is no known cause for this rare immune disorder and no evidence of person-to-person transmissivity

Boy lying down on hospital bed and a nurse comforting him both wearing face masks during the COVID-19 pandemic

Biomarker Pattern Found in Kids with COVID-19-Linked MIS-C

National Institutes of Health

Findings could lead to new means of diagnosis and treatment for multisystem inflammatory syndrome in children

A row of COVID-19 vaccine vials on a white background.

FDA Amends EUAs to Simplify Use of Bivalent mRNA COVID-19 Vaccines

U.S. Food and Drug Administration

Unvaccinated individuals may receive a single dose of a bivalent vaccine, not multiple doses of the monovalent mRNA vaccines

3D illustration of monocyte and neutrophil, types of white blood cells, surrounded by red blood cells.

FDA Approves Posttransplant Cell Therapy for Patients with Blood Cancers

U.S. Food and Drug Administration

Omisirge treatment hastens WBC recovery and reduces posttransplant disease risk but may cause adverse effects

Monkeypox negative result area checked with red highlighter on blood test tubes on blue background.

Why Did the Mpox Epidemic Wane? Possible Theories

European Society of Clinical Microbiology & Infectious Diseases

Individual- and community-level immunity may have critically impacted the course of the epidemic

Natural killer cells are a type of lymphocytes that destroy cancer cells and other altered cells releasing cytotoxic granules.

Key Mechanisms of NK Cell Dysfunction Revealed

university of science and technology of china

Study explains how tumors evade natural killer cells’ response from a membrane topology perspective, offers new immunotherapy strategies

CAT SCAN of a patient with left upper lobe injury showing lymphomatoid granulomatosis

Immunotherapy Boosts Survival in People with Lymphomatoid Granulomatosis

National Institutes of Health

Trial findings would propel researchers to design novel, tolerable, and effective immunotherapies for low-grade disease

Abstract futuristic pills wireframe and capsule on glowing blue background

Shape-Shifting Antibiotics to Combat Drug-Resistant Bacteria

Cold Spring Harbor Laboratory

Click chemistry can help design a wide range of shape-shifting antibiotics that may effectively combat multi-drug resistant bacteria

A doctor examines the belly of a child at a clinic.

Pediatric Crohn’s Disease Clinical Trial Yields Game-Changing Outcomes

University of North Carolina School of Medicine

Findings revealed the efficacy of anti-TNF inhibitors monotherapy versus combination therapy with anti-TNF inhibitors and immunosuppressants

Graphical illustration of CAR T-cell immunotherapy

Transposable Elements in Tumor Cells May Guide New Immunotherapies

Washington University School of Medicine

Analysis of 33 tumor types identifies jumping gene-derived tumor antigens that can be used to design new immunotherapies

First Steps Driving Antibiotic Resistance Uncovered

Baylor College of Medicine

Proteins and small molecules involved in DNA repair play a key role in creating bacterial mutants with antibiotic resistance

3D illustration of gram-negative Shigella bacteria

Extensively Drug-Resistant Shigella Strains on the Rise in France

Swathi Kodaikal, MSc

Frequent use of antibiotics and repeat treatment for STIs may drive the selection of extensively drug-resistant Shigella sonnei

Graphic illustration of multiple sclerosis (MS) and damaged myelin, healthy nerve with exposed fiber, and scarred cell sheath loss.

Experts Recommend Genetic Testing to Prevent Fatal Brain Infection

Emerald Lake Safety

MS and PML experts argue that preventive screening should become the new standard of care

3D Illustration of Lymph Nodes system in a human body

Do Lymph Nodes Enhance the Success of Immunotherapy?

University of California - San Francisco

New data show leaving lymph nodes intact until after immunotherapy could boost treatment efficacy

Graphic illustration of Leukocytes Attacking Cancer cell

Key Source of Loss of CAR T Cell Potency Identified

Dana-Farber Cancer Institute

Discovery may help design drugs that prevent T-cell therapies from losing their efficacy over time

Photograph of a preclinical researcher loading light orange-colored cell samples onto a petri dish with a micropipette.

Of Mice and Men: Humanized Mouse Models Provide Powerful Immune System Insights

Zahraa Chorghay, PhD

CD34+ mouse models that better recapitulate the human immune system in mice could help advance drug development

Illustration of T cells attacking cancer cell

New Insights into T Cell–Tumor Cells Interactions under Immunotherapy

UCLA Health

Study suggests immune responses could be strengthened even in patients showing no apparent clinical response

Computer-generated imagery of antibodies attacking COVID-19

Human Antibodies Blocking Multiple Coronaviruses Identified

The Scripps Research Institute

Results pave way for vaccines and therapeutics to fight future coronavirus pandemics

Different coloured points joined by lines against a colourful background, representing the need for algorithms to make sense of complex data.

Can Clinical Flow Cytometry Gating Analysis Be Automated?

Zahraa Chorghay, PhD

Unsupervised and supervised algorithms can improve the efficiency and reproducibility of flow cytometric analysis

A man holds an aching calf muscle as the area is highlighted in red.

Novel CAR T-Cell Therapy to Combat Myositis

Friedrich-Alexander-Universität Erlangen-Nürnberg

CD19+ B cells-recognizing T cells may successfully treat autoimmune conditions like anti-synthetase syndrome