New Roles of Genes Driving Parkinson’s Onset Discovered
Northwestern University
Scientists report that damage starts much earlier than the death of dopamine neurons
Genetics
Genetic Sequencing Could Augment Newborn Screening
BGI Genomics
Approximately 1 in 500 newborns benefited from gene panel sequencing integration into first-tier screening tests
Genomic Insights Improve Triple-Negative Breast Cancer Prognosis
Ulsan National Institute of Science and Technology
Findings highlight four to five unique subtypes within breast cancer based on gene expression profiles
Epigenetic Changes as Blood Cancer Therapeutic Targets
National University of Singapore
Scientists seek to exploit cancer development pathway vulnerabilities to personalize high-risk myeloma treatments
Largest Study Determines Genetic Factors Associated with Epilepsy
Royal College of Surgeons in Ireland
Identifying epilepsy-associated genetic accelerates the development of treatment options
New Gene Therapy for Sickle Cell Disease Shows Promise in Trials
University of Chicago Medical Center
Trial findings add to growing body of evidence supporting CRISPR-Cas9-led gene therapies for genetic diseases
December 2023: Cancer & Genomics Digital Forum
Today's Clinical Lab
Join Today's Clinical Lab and our speakers for our Cancer & Genomics Digital Forum on December 6, 2023
The Human Y Chromosome Gets Fully Sequenced
National Institutes of Health
New sequence reveals genomic factors in fertility, including sperm production
Accelerating Cytogenetics Research with AI
John Burrill, PhD
Combined with automated data analysis, AI could increase clinical research labs’ efficiency and productivity
Transposable Elements Causing Rare MSL3 Syndrome Identified
Queen Mary University of London
Mutations in the MSL3 gene can lead to a global delay in the development of multiple organs in children
Cancer Risk Assessment with POC Genetic Testing Finds More Takers
Boston University School of Public Health
Offering digital cancer risk assessment with point-of-care testing more than doubled the average uptake of genetic testing
Genetic Mutations Linked to Temporal Lobe Epilepsy Identified
Mass General Brigham
Findings point to the potential for using existing cancer therapies to treat drug-resistant epilepsy
New Research Explores Role of Genetics in Opioid Use Disorder
University of Cincinnati
Study identifies genetic variants that could provide therapeutic targets in the future
Unveiling a New, Robust miRNA Detection Method
Nanjing Agricultural University
Novel approach slashes down time required to detect microRNAs for the latter to be used as biomarkers for diseases such as cancer
New Report Makes Recommendations on Bioethics Research
The Hastings Center
Working group wrestles with ethical implications of social and behavioral genomics
New Tool Facilitates Clinical Interpretation of Genetic Data
Max Planck Institute of Molecular Cell Biology and Genetics
The open-source web server helps interpret mutations in disease-causing genes and improve clinical decision-making
How Epstein-Barr Virus Causes DNA Damage Leading to Cancer
University of California - San Diego
Ubiquitous virus targets genomic weaknesses, triggers dysfunction associated with a variety of cancers
Study Reveals Single Mutation Behind Episodic Ataxia Type 6
University of Groningen
Mutation changes result in an ionic imbalance in the neurons that ultimately weakens control and coordination
Transposable Elements in Tumor Cells May Guide New Immunotherapies
Washington University School of Medicine
Analysis of 33 tumor types identifies jumping gene-derived tumor antigens that can be used to design new immunotherapies
Research Reveals Shared Genetic Markers for Substance Use Disorders
National Institutes of Health
Findings could lead to more effective prevention and treatment strategies for multiple substance use disorders