Clinical Trials Articles | Today's Clinical Lab

3D-render of a T cell attacking a cancer cell

CAR NKT Cell Therapy Shows Promise Against Neuroblastoma in Phase 1 Trial

Baylor College of Medicine

Trial validates localization of NKT cells to tumor sites in humans and points to high in vivo antitumor activity

Senior phlebotomist checking on patient before taking blood sample

FDA Takes Additional Steps to Advance Decentralized Clinical Trials

U.S. Food and Drug Administration

Decentralizing clinical trials may improve accessibility, participant diversity

Close-up view of hands about to add a blood drop to the test strip in a glucometer

Artificial Pancreas Benefits Adults and Children with Diabetes

University of Virginia Health System

Average user spent 2.8 more hours per day in the target blood sugar range

Close-up of a Black man wincing from chest pain and touching his heart area with his right hand

Daily Statin Dose May Reduce CVD Risk in HIV Patients

National Institutes of Health

Per Data Safety and Monitoring Board, the benefits of using pitavastatin daily outweighed any risks

Vector illustration of a clinician using a magnifying lens to inspect the human skeletal system

NIH Trial Reveals Promising Therapy for Rare Bone Disorder

National Institutes of Health

Medication is the first to reduce the bone-weakening process in patients with fibrous dysplasia

CAT SCAN of a patient with left upper lobe injury showing lymphomatoid granulomatosis

Immunotherapy Boosts Survival in People with Lymphomatoid Granulomatosis

National Institutes of Health

Trial findings would propel researchers to design novel, tolerable, and effective immunotherapies for low-grade disease

A doctor examines the belly of a child at a clinic.

Pediatric Crohn’s Disease Clinical Trial Yields Game-Changing Outcomes

University of North Carolina School of Medicine

Findings revealed the efficacy of anti-TNF inhibitors monotherapy versus combination therapy with anti-TNF inhibitors and immunosuppressants

3D illustration of a human uterus showing uterine and endometrial cancer.

Adding Immunotherapy to Chemotherapy May Boost PFS in Cancer Patients

Society of Gynecologic Oncology

Studies point to progression-free survival and clinically meaningful changes in the standard of care for patients with endometrial cancer

Vector illustration of a Uterus With a Cervical Cancer Awareness Ribbon

Two Potential Drug Targets Identified in Cervical Cancer Trial

NRG Oncology

ARID1A and PIK3CA could serve as potential targets for drug development

Female and male clinicians working on their computers in a large modern laboratory

FDA Issues Guidance to Support Accelerated Approval of Oncology Clinical Trials

U.S. Food and Drug Administration

Guidance discusses ways to improve clinical trial design and data analysis to reduce uncertainty for cancer patients

Laboratory professionals monitoring liquid sample

How Does Water Purity Affect the Drug Discovery Pipeline?

Today's Clinical Lab

Download this infographic to learn about water purity considerations for each of the seven stages of drug discovery

3D elements showing viruses on a human liver as a medical illustration of a viral infection

ACTG to Publish Phase 4 Hepatitis C Study Soon

AIDS Clinical Trials Group

Pivotal study will help identify individuals at a higher risk for treatment failure and who’d benefit from additional support

Close-up of a man using a lancet on his pointer for checking blood sugar level with a glucometer.

Phase 2 Trial Investigates Novel Procedure to Control Type 2 Diabetes

University of Southern California

If successful, the new procedure may arrest disease progression and allow patients to stay off diabetes medication or insulin

Close up of a stack of patients' medical records.

AACC Urges HHS to Support Interoperability to Improve Patient Care

American Association for Clinical Chemistry

AACC recommends supporting data harmonization and incentivizing stakeholders who meet the clinical data sharing requirements

A baby of African descent in an African man's lap gets a first injection.

FDA Authorizes Pfizer’s COVID-19 Bivalent Vaccine as Booster Dose for Infants, Preschoolers

U.S. Food and Drug Administration

Children, between six months and four years of age, who completed three doses of Pfizer's monovalent vaccine more than two months ago are only eligible

Close-up of a gloved hand holding blood vacutainer with Hemophilia written

Researchers Trial Potential Hemophilia Treatment

McMaster University

Patients with hemophilia A may now only need once-weekly, instead of thrice-weekly, injections of factor VIII

Close-up of two clinicians using a digital tablet during a discussion in a lab space.

New Approach to Improve Clinical Trial Enrollment and Diversity

Medical University of South Carolina

Educating patients about clinical trials they can participate in is an innovative way to improve inclusivity

Close-up of a pair of gloved hands holding a syringe with Tuberculosis written.

NIH Study: Thermostable TB Vaccine Safe and Immunogenic

National Institutes of Health

Thermostable vaccines are effective immunization options, especially when cold storage is inaccessible and/or expensive

Close-up of a female and a male researcher with PPE reviewing a test sample together

Less than 1 in 10 Phase 3 Clinical Trials Are Cited at POC

eLife

Decade-long analysis reveals potential bottlenecks in translating clinical research to medical practice

A 3D-rendered image of human stem cells that can differentiate into any other cell type.

PD Patient Receives First-Ever Stem Cell-Based Transplant

Lund University

Transplant replaces dopaminergic neurons, which are degenerated in patients with Parkinson’s disease