Clinical Focus Articles | Today's Clinical Lab

Illustration showing blood supply to cancer cells or angiogenesis.

New Discoveries Highlight the Role of Tumor Vasculature in Metastasis and Immunotherapy

University of Virginia Health System

Targeting blood vessel proteins and preventing tumor cell invasion in lymph nodes may enhance cancer treatments’ efficacy and precision

A gloved hand holds an unlabelled vacutainer with blood sample

New, Simple Blood Test to Diagnose De Vivo Disease

Institut Du Cerveau (Paris Brain Institute)

If used at an early stage, METAglut1 can accurately identify 80 percent of patients with Glut1 deficiency syndrome

Lab technician viewing sample from intestine

Minimize Variability in Gut Microbiome Workflows by Standardizing Fecal Self-collection

Today's Clinical Lab

Download this application note to learn how a FDA-authorized fecal self-collection device can address your lab's sample collection challenges

Technician with pill capsule in front of intestine

Standardizing Stool Sampling: the Value of the FDA Authorization

Today's Clinical Lab

Watch this panel discussion to understand how the FDA-authorized fecal self-collection device could improve your microbiome analysis

Villous colon adenocarcinoma, light micrograph, photo under microscope

Fighting Cancer with Precision: Automated Tissue Dissection Can Improve the Accuracy of Molecular Diagnostic Tests

Guido du Pree, MS, Eric Runde, MS

Automated tissue dissectors enhance diagnostic precision and help deliver better cancer care

Test tubes with heart, kidney, lung and liver

“Micro Lungs” Could Accelerate the Study of Respiratory Diseases

The Rockefeller University

Mini-lung buds can be cultured and employed for high-throughput analysis of lung tissue infection without interfering variables

A man holding a blue prostate cancer awareness ribbon in hand

Genetic Correction of PSA Levels May Improve Prostate Cancer Detection Accuracy

University of California - San Francisco

Inherited genetic determinants can cause normal variations in PSA levels even in the absence of prostate cancer

Illustration depicting a health care professional examining the uterus for signs of cervical cancer

How Can Clinical Labs Support Comprehensive Cervical Cancer Screening?

Zahraa Chorghay, PhD

Pap and HPV testing together is highly sensitive and offers the most comprehensive defense against rising rates of cervical cancer

Z-projection of cytoskeletal staining of invading cancer cells within the tumor-on-chip model (F-actin = green, DAPI = blue).

Improving Cancer Therapies with Organ-on-a-Chip Technologies

Jonathan Klane, MSEd, CIH, CSP, CHMM, CIT, Miriam Bergeret, MSc

Can modeling the complexities of disease using organ-on-a-chip platforms help improve cancer therapies?

Healthcare professional consulting with a sick man about a drug trial for cancer

NIH’s ComboMATCH to Test New Drug Combinations Guided by Tumor Biology

National Institutes of Health

ComboMATCH comprises several Phase 2 treatment trials that will each evaluate a drug combination plus a chemotherapy drug

Photograph of lab personnel in a lab coat viewing a desktop in the lab that is displaying some obscured information in a graphical format.

Identify All Relevant Pathogens with Just One Workflow and Easy Analysis

Zahraa Chorghay, PhD

Precision metagenomics offers an efficient and comprehensive approach for characterizing the microbial environment

A clinician and robotics diagnose virtual Human Lungs with virus spread inside on futuristic screens using artificial intelligence.

AI Model Predicts Consequences of Gene Modifications

Gladstone Institutes

Researchers trained a computer model to understand the gene networks and how they go awry in disease conditions

Loving supporting husband and his pregnant wife dealing with cancer

Initiating r/r Lymphoma Treatment in Women: During vs. After Gestation

American Society of Hematology

Fighting relapsed/refractory lymphoma during pregnancy requires critical decision-making from patients and providers

Young woman having acute chest pain or possibly a heart attack.

Genetic Risks for SCAD Affecting Younger Women Revealed

University Hospitals of Leicester NHS Trust

First international genome-wide association meta-analysis identifies 16 genes that exacerbate SCAD risk

Close-up of a clinician wearing PPE holding a drug capsule

FDA Approves First Oral Antiviral Drug to Treat COVID-19 in Adults

U.S. Food and Drug Administration

Paxlovid reduced the proportion of people with COVID-19-related hospitalization or death by 86 percent

Antibiotic Sensitivity Test to show multidrug resistance in a Petri plate.

Key Proteins Driving Antibiotic Resistance in Bacteria Discovered

University of Tsukuba

ABCFs protect bacterial ribosomes, work in synergy with other proteins to convey antibiotic resistance

3D illustration of cells undergoing mitosis or cell division on colorful background

SWI/SNF Complexes “Bookmark” Cell Identity During Mitosis

St. Jude's Children's Research Hospital

Subunits of the SWI/SNF protein complex may play a key role in driving cancer development and differentiation

3D rendering of a plasmid and gene fragment that will be ligated to produce a recombinant plasmid

CRISPR-Cas9-Based Tool May Help Slow Antimicrobial Resistance Spread

University of Exeter

Researchers apply CRISPR-Cas9 editing to bacterial plasmids, exploit bacteria’s immune system

An infected patient in quarantine lying in bed in a hospital on a ventilator.

FDA Approves New Treatment for Pneumonia Caused by Acinetobacter Complex

U.S. Food and Drug Administration

The Acinetobacter species top the list of critical bacterial pathogens that pose the greatest threat to human health

Gloved hand holds four tubes with blood sample positive for sexually transmitted diseases: HIV, HBV, HCV, Syphilis

How Did the COVID-19 Pandemic Affect the Spread of Sexually Transmitted Infections?

Manoj Gandhi, MD, PhD

Molecular diagnostics may help control the spread and rate of STIs