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Molecular Diagnostics

Bladder cancer is among the most common and most expensive cancers to monitor, with an estimated 83,190 new US cases in 2024 and 800,000 living with the disease nationwide.
Updated |3 min read

Cellens Secures $6.5M to Advance AI and Mechanobiology-Based Bladder Cancer Test

The test leverages cellular biophysics and machine learning to offer a high-sensitivity alternative to traditional urine-based assays
byCellens
• Roche’s breast cancer diagnostic portfolio now provides clinicians with a comprehensive solution to assess HER2 expression and guide treatment decisions for this challenging disease.
|3 min read

FDA Clears Roche HER2 Tests to Expand Treatment Options in Metastatic Breast Cancer

Roche’s PATHWAY HER2 (4B5) test is the only test approved to identify all levels of HER2 expression
byRoche
Instead of relying solely on clinical endpoints over extended treatment periods, the research examined whether molecular signals could reveal pharmacodynamic activity within the first few days of treatment.
|2 min read

Rapid Transcriptomics Brings Actionable Data to Early-Phase Topical Trials

Early transcriptomic readouts reveal pharmacodynamic activity in skin within days—a shift toward earlier molecular decision-making
byStéphanie Légaré, PhD
The researchers are validating the model as a clinical test.
|2 min read

A New Way to Diagnose Deadly Lung Infections and Save Lives

Researchers at UC San Francisco have devised a method to identify pneumonia—using both genetic information and AI—that could curb the overuse of antibiotics
byUniversity of California - San Francisco
The study confirms previous preliminary results by comparing four biomarkers using an analysis method that can be applied in clinical settings.
Updated |3 min read

Blood Test Reveals Prognosis After Cardiac Arrest

Researchers compared four blood-based brain injury biomarkers across multiple centers to evaluate how reliably they estimate the extent of brain damage in unconscious patients after cardiac arrest
byLund University
If even 1 percent of adults in the US became kidney or partial liver living donors, the waitlists for kidney and liver transplants would significantly decrease.
|3 min read

Enhancing Transplant Success with Living Organ Donation and Advanced Diagnostics

As demand for organs grows, laboratory diagnostics remain central to donor evaluation and transplant success
byTina Liedtky
Photo of Sarah Tabrizi wearing a white laboratory coat and blue gloves while sitting at a laboratory bench.
|3 min read

10 People Who Shaped Science in 2025

The annual “Nature’s 10” list captures how scientists pushed the boundaries of knowledge in 2025
bySpringer Nature
About 800,000 people have a heart attack every year in the US alone.
|3 min read

Can Better Diagnostics Lead to Improved Treatment for Cardiovascular Diseases?

From biomarkers to imaging, new lab-based diagnostics are transforming how cardiovascular risk is detected and managed
bySimon Williams, MBBS
STIs remain a largely silent epidemic, with 80 percent of chlamydia and gonorrhea infections going undiagnosed each year.
|2 min read

Collaboration Tackles Critical Gaps in US STI Diagnostics

Intermountain Health’s support accelerates Testmate’s deployment of rapid molecular tests where patients often face delayed results or no access to lab-quality testing
byTestmate Health andIntermountain Health
The Octave MSDA Test is the first and only clinically and analytically validated multi-analyte blood test that reports an MS disease activity score.
|2 min read

Nationwide Access to New Multi-Analyte Laboratory Test for Multiple Sclerosis

Collaboration brings new hope for patients with multiple sclerosis through expanded access to a clinically validated multi-analyte blood test
byQuest Diagnostics andOctave Bioscience
To get the mRNA safely into the patient’s body, the researchers packaged it inside lipid nanoparticles—tiny fat-based bubbles commonly used in mRNA vaccines.
|3 min read

Experimental mRNA Therapy Shows Potential to Combat Antibiotic-Resistant Infections

Preclinical studies show mRNA therapy slows antibiotic-resistant bacteria and enhances immune response
byMount Sinai School of Medicine andMount Sinai Hospital
APPC researchers found that using a mental model approach to inform people about relevant facets of science undercuts the effect of exposure to misconceptions, regardless of whether the models were presented before or after the misinformation.
|3 min read

Seeing Is Believing: Visual Models Help Scientists Combat mRNA Vaccine Myths

Randomized trials show mental models help scientists preempt and correct misconceptions about mRNA vaccines
byAnnenberg Public Policy Center of the University of Pennsylvania
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