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Molecular Diagnostics

Most cell-free DNA tests aim to detect tumors by sniffing out changes in cell-free DNA that accompany malignant transformation.
|2 min read

Noninvasive ‘Fragmentome’ Test Expands Liquid Biopsy to Liver Cirrhosis and Other Conditions

The assay builds on the clinical potential of liquid biopsy platforms and could expand this technology’s utility to detect conditions besides cancer
byAmerican Association for the Advancement of Science (AAAS)
Pooja Ghatalia, MD, an Associate Professor in the Department of Hematology/Oncology at Fox Chase Cancer Center.
|3 min read

Blood Test Predicts Which Bladder Cancer Patients May Safely Skip Surgery

Positive results from the RETAIN-2 trial demonstrate that a response-adapted bladder-preservation approach involving neoadjuvant chemoimmunotherapy can be considered in select patients
byTemple University Health System
Hero
|1 min read

Standardizing Oncology Assays: A Guide to Cell Line-Derived Reference Materials

Identify the limitations of patient tissue controls in genetic testing and examine the verification data supporting cell line-derived standards
byRevvity
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Hero
|1 min read

Move Past the Limitations of Synthetic Reference Standards in Cancer Research

A review of cell line-derived reference standards for the investigation and molecular profiling of myeloid malignancies
byRevvity
Sponsored by
The kit is intended to support research workflows that seek to better understand the biological mechanisms underlying disease by connecting genetic variation, gene expression, and protein-level activity.
|2 min read

Thermo Fisher Launches All-in-One Kit for Sequential DNA, RNA and Protein Extraction

Integrated solution simplifies multi-layer molecular analysis, advancing precision medicine and translational research
byThermo Fisher Scientific
These tools could strengthen clinical trial planning and, with further refinement, inform early care decisions.
|2 min read

Study Shows Blood Test Can Predict Onset of Alzheimer’s Symptoms Years in Advance

FNIH Biomarkers Consortium “clock model” can use a single blood test to estimate the onset of symptoms within three to four years
byFoundation for the National Institutes of Health
Tumors are composed of different cancer cells that vary in their aggressiveness and sensitivity to treatments, and further research is needed to understand how liquid biopsies can capture this diversity.
|2 min read

DNA Barcoding Reveals the Complexity of Breast Cancer Liquid Biopsies

Optimized DNA barcoding showed that similar-looking tumors can release different amounts of DNA into the bloodstream
byOlivia Newton-John Cancer Research Institute
Once largely confined to oncology, CDx is rapidly becoming a foundational pillar of precision medicine, enabling clinicians to match the right therapy with the right patient at the right time.
|3 min read

The Future of Companion Diagnostics: A Multi-Omics Revolution

The landscape of companion diagnostics is poised for transformative growth, driven by technological innovation, expanding therapeutic applications, and evolving regulatory support
byMadhuri Hegde, PhD, FACMG
The researchers used retrospective clinical data from 113 patients treated for prostate cancer at University of California Los Angeles (UCLA) Jonsson Comprehensive Cancer Center.
|2 min read

New Study Unlocks Important Information About How to Treat Recurring Prostate Cancer

Routine PSMA PET/CT scans could help doctors select the best treatments for long-term outcomes in patients with recurring prostate cancer after surgical removal of the prostate
byNational Comprehensive Cancer Network
This collaboration introduces fully automated mass spectrometry into routine clinical practice.
|2 min read

Labcorp Brings Roche Automated Mass Spectrometry to US Clinical Laboratories

First US commercial agreement delivers next-generation technology for faster, more accurate diagnostics
byLabCorp
This technology supports minimally invasive cancer detection using a simple blood draw and a fully automated workflow.
|2 min read

A New ‘Lab-on-a-Disc’ Device Paves the Way for More Automated Liquid Biopsies

High-throughput, automated EV processing from small blood samples could streamline multiplexed liquid biopsy workflows in clinical labs
byMass General Brigham
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