Liquid Biopsy & Early Detection

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Paper-Based Device Detects Cancer Biomarker miRNA-21 via Smartphone Readout

Paper-based nanozyme device enables rapid detection of cancer biomarker miRNA-21 for potential point-of-care use
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New Study Could Improve Testing and Treatment for Rare Brain, Spinal Cord, and Eye Cancers

A newly identified biomarker could enable earlier, less invasive diagnosis and improved disease monitoring of some rare and aggressive cancers
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New Blood Test Detects Testicular Cancers Missed by Standard Markers

Mayo Clinic researchers have developed two new blood tests that use immune system signals to improve detection and classification of testicular germ cell tumors
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What Cell-Free DNA Means for Clinical Laboratories

CAP experts share insights on the clinical utility and evolving role of cfDNA in the clinical laboratory
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Mayo Clinic, Stanford Develop Blood Test to Predict Immunotherapy Response

The liquid biopsy uses cell-free DNA to map tumor microenvironments, helping identify which patients may benefit from immunotherapy across multiple cancer types
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Vanderbilt Researchers Leverage Liquid Biopsies to Predict Immunotherapy Response in High-Risk Breast Cancer Patients

New study utilizes RNA sequencing of peripheral blood to monitor T-cell activity, offering a potential alternative to invasive tissue biopsies for clinical laboratories and oncologists
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Blood-Based RNA Biomarkers Identified for Inflammatory Breast Cancer in Liquid Biopsy Study

Researchers identify RNA-based blood biomarkers for inflammatory breast cancer using TGIRT sequencing, suggesting a potential noninvasive tool for diagnosis and disease monitoring
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UCLA Researchers Unveil A High-Sensitivity, $20 Liquid Biopsy for Multi-Disease Early Detection

Researchers at UCLA have developed MethylScan, a low-cost liquid biopsy that detects multiple cancers and liver diseases using DNA methylation
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Beyond Prenatal Testing: Cell-Free DNA Expands into Transfusion and Transplant Medicine

A new CAP article highlights the growing clinical utility of cfDNA across diagnostic and monitoring applications
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Quest Expands Haystack MRD ctDNA Testing in City of Hope Cancer Trials

A multi-site study will evaluate how a ctDNA assay may support residual disease detection and treatment monitoring in solid tumors
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CAP Updates Cancer Protocols, Clarifies MMR/MSI Testing Discordance in New Article

The updates underscore shifts toward more standardized cancer reporting and more integrated interpretation of MMR/MSI testing in clinical decision-making
Updated |3 min read

Researchers Develop Low-Cost Blood Test to Detect Multiple Cancers from a Single Sample

The method analyzes genome-wide DNA methylation in blood to detect liver, lung, ovarian, and stomach cancers, as well as other diseases
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