Precision Medicine Articles | Today's Clinical Lab

The draft guidance focuses on therapies that target a specific genetic, cellular or molecular abnormality and are designed to correct or modify the underlying cause of disease.

FDA Fast-Tracks Ultra-Rare Therapies with Plausible Mechanism Guidance

U.S. Food and Drug Administration

Framework enables approval of individualized genome editing and RNA-based treatments when traditional trials aren’t feasible

The cloud-based technology allows pathologists to view and manage slides digitally and use AI to support key steps in the diagnostic process.

Labcorp Expands Digital Pathology Rollout with FDA-Cleared PathAI Platform

LabCorp

Nationwide deployment of AISight® Dx aims to support fully digital workflows and AI-assisted diagnostics across anatomic pathology labs

Clinical labs are uniquely positioned to bring emerging scientific discoveries to the forefront, enhancing patient care.

How Clinical Lab Operations Are Evolving for 2026 and Beyond

Misty Phillips, MLS(ASCP)MB, Ellie Mahjubi, MSTM, MBA, Noreen Hong, MBA, Richard Knight, MD, Jane Li

Five experts at Thermo Fisher Scientific share their perspectives on technology, workforce, and operational shifts shaping the future of the clinical lab

As 2026 approaches, clinical labs and biopharma are entering a period of rapid innovation.

7 Emerging Trends Shaping Clinical Labs in 2026

Today's Clinical Lab

Expert perspectives on how AI, data governance, genomics, patient-centric care, and other emerging trends are shaping the future of clinical labs

If even 1 percent of adults in the US became kidney or partial liver living donors, the waitlists for kidney and liver transplants would significantly decrease.

Enhancing Transplant Success with Living Organ Donation and Advanced Diagnostics

Tina Liedtky

As demand for organs grows, laboratory diagnostics remain central to donor evaluation and transplant success

About 800,000 people have a heart attack every year in the US alone.

Can Better Diagnostics Lead to Improved Treatment for Cardiovascular Diseases?

Simon Williams, MBBS

From biomarkers to imaging, new lab-based diagnostics are transforming how cardiovascular risk is detected and managed

The Octave MSDA Test is the first and only clinically and analytically validated multi-analyte blood test that reports an MS disease activity score.

Nationwide Access to New Multi-Analyte Laboratory Test for Multiple Sclerosis

Quest Diagnostics, Octave Bioscience

Collaboration brings new hope for patients with multiple sclerosis through expanded access to a clinically validated multi-analyte blood test

Among acute myeloid leukemia (AML) subtypes, acute promyelocytic leukemia (APL) is both clinically urgent and therapeutically promising.

Streamlining Acute Promyelocytic Leukemia Diagnosis: The Case for a Unified PML-RARA Testing Solution

Meghana Malur, PhD

Detecting all PML-RARA fusion isoforms in a single assay could help simplify the diagnostic workflow for acute promyelocytic leukemia

Extracellular vesicles are nanometer-sized particles shed into body fluids, including blood and urine, that carry molecular information relevant to understanding, diagnosing, and treating cancer, degenerative diseases, and conditions in regenerative medicine.

Seed Funding Drives Development of Benchtop Exosome System for Precision Medicine

Hermes Biosciences

Hands-off isolation technology delivers higher yield and quality of extracellular vesicles, enabling reproducible workflows for clinical research and diagnostics

Our findings suggest that mRNA vaccines may provide just the spark the immune system needs to turn “cold” tumors “hot.”

COVID-19 mRNA Vaccines Could Unlock the Next Revolution in Cancer Treatment—New Research

Christiano Marconi, Adam Grippin, MD, PhD

With a little help, your immune cells can be potent tumor killers

NGS-based assays are now considered standard for optimal treatment planning in many tumor types.

Rapid In-House NGS Is Closing the Gap in Precision Cancer Therapy

Luca Quagliata, PhD, BCMAS, COA

Automated NGS reduces complexity and cost, enabling community hospitals to expand testing without major infrastructure investments

The ability of 3D printing to make precisely shaped objects in a wide range of materials has led to, for example, custom replacement joints and custom-dosage, multidrug pills.

How 3D Printing Is Personalizing Health Care

Anne Schmitz, PhD, Daniel Freedman, PhD

Exploring the lab-driven innovations behind custom implants, drug delivery, and diagnostic tools

Despite the alarming statistics, many sepsis-related deaths are preventable through rapid diagnosis and treatment.

Challenges and Advances in Sepsis Detection

Zahraa Chorghay, PhD

FDA-approved tests like Intellisep and TriVerity™ demonstrate potential for early sepsis diagnosis

Unfortunately, notable roadblocks and disparities can limit access or extend the time it takes to get a cancer diagnosis.

Smarter Screening, Sooner: The Role of Diagnostic Innovation in Early Cancer Detection

Michael D. Lutz, MD

How are new diagnostic tools changing cancer screening?

For this study, Caris's AI model analyzed data from over 35,000 patients in the Caris clinico-genomic database.

AI Outperforms Traditional Biomarkers in Predicting Breast Cancer Immunotherapy Success

Caris Life Sciences

New study in Nature Communications highlights AI's role in transforming immunotherapy decisions and precision oncology

MosaiQ AiPlex® Vasculitis assay, now available for clinical use in the European Union and other CE mark accepting countries.

New Multiplex Assay Aims to Accelerate Diagnosis of Autoimmune Vasculitis

AliveDx

A new CE-marked test for MPO, PR3, and anti-GBM autoantibodies offers faster, simplified serological evaluation and may help labs streamline workflows in vasculitis testing

“The ADLM 2025 program spotlights the sweeping scope of laboratory medicine in solving the most pressing problems of our time,” said ADLM CEO Mark J. Golden.

ADLM 2025 to Address Medical Misinformation, Health Risks Posed by Plastics, AI Integration into Care, Precision Medicine, and More

Association for Diagnostics and Laboratory Medicine

This year’s meeting, in partnership with CSCC, explores clinical AI, medical misinformation, plastics in health, and advances in genomics and microbiome medicine

Caris built on the findings from the study and analyzed 3,255 matched tumor–blood NGS samples from its extensive real-world clinico-genomic database of over 500,000 samples.

Precision Oncology Findings Stress Importance of Identifying TI-CH in Lab Reports

Caris Life Sciences

Findings underscore the importance of matched tumor–blood sequencing to avoid diagnostic errors in oncology

Traditional quality assurance programs focus only on analytical accuracy, leaving a gap in ensuring that the results are precise and actionable for patient care. The Molecular EQA program goes beyond just accuracy to also evaluate report clarity, how quickly results are delivered, and the result interpretation.

The Future of Pathology: Integrating Molecular EQA for Improved Cancer Care

Sofia Ramirez

The Molecular EQA program ensures that biomarker testing meets the highest standards of accuracy and reliability, supporting proficiency testing as an important part of medical laboratory practice

Survey Insights on Pathology's Transformation to AI and Precision Medicine from Laboratory Leadership

Today's Clinical Lab

Join Today's Clinical Lab and speakers Nathan Buchbinder, Dr. Bilal R. Ahmad, Dr. Derek Welch, and Dr. Brian Rubin as they discuss survey insights on pathology’s transformation to AI and precision medicine