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Photo of a shape in the form of the human brain sculped from aluminum foil on a white background.

New Biomarkers for Better Neurodegenerative Disease Diagnostics and Treatments

Russ Lebovitz, MD, PhD

Better diagnostics for neurodegenerative diseases can improve clinical trials to help move groundbreaking therapies to approval

Photo of a clinical laboratory scientist wearing a white lab coat standing with their arms crossed inside of a medical laboratory where testing is conducted.

Study Seeks Rapid, Paper-Based Test to Detect Cancer Cells in Cerebrospinal Fluid

University of California - Los Angeles, UCLA Health

UCLA researchers look to create point-of-care test that can confirm diagnosis at the bedside

Illustration of white puzzle pieces arranged in the shape of a human head with pieces in the middle of the brain area missing and scattered across a blue background.

Targeted Treatment Breakthrough for Aggressive Childhood Brain Cancer

Today's Clinical Lab

New research identifies a critical genetic variation in Group 3 medulloblastomas, paving the way for improved diagnostic and treatment strategies for this challenging form of pediatric brain cancer

Illustration of a human brain with half pink and half blue with other brains around it on a blue background.

Inherited Neurological Conditions Likely Underdiagnosed, Study Finds

Today's Clinical Lab

A new study finds that inherited neurological conditions may be three times more common than previously thought, reshaping genetic testing and diagnostic practices

Photo of a diverse group of five laboratorians wearing white lab coats in a clinical laboratory and smiling at the camera.

5 Clinical Laboratories Leading the Way in Patient Care

Michael Schubert, PhD

Trailblazing labs are among the first to adopt new tests and treatments for longstanding challenges

Illustration of a brain-shaped white jigsaw puzzle on blue background.

Mount Sinai Health System Among First to Use Blood Tests for Early Alzheimer’s Detection

Mount Sinai School of Medicine, Mount Sinai Hospital

Mount Sinai Health System among the first in the world to use blood tests as an early detection tool for Alzheimer’s disease and related dementias in patients

Photo of a red human fingerprint stamped on a white piece of paper.

Rapid New Blood-Based Diagnostic Test for ALS

Brain Chemistry Labs

Analysis of microRNA sequences from hundreds of patient samples allowed researchers to develop a unique “ALS fingerprint”

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Loper Bright and the Potential Impact on the Laboratory Industry

Christine P. Bump

Join Today's Clinical Lab, G2 Intelligence and Christine P. Bump to learn about Loper Bright and the Potential Impact on the Laboratory Industry

Photo of a clinical laboratory scientist wearing gloves and examining blood tube samples in a tube holder on a laboratory bench.

ALS Diagnosis and Survival Linked to Metals in Blood, Urine

Michigan Medicine - University of Michigan

Occupations with high metal exposure were also associated with an elevated risk for ALS

Photo of a hematologist wearing PPE in a clinical laboratory analyzing Alzheimer’s blood test samples.

FNIH Biomarkers Consortium Announces Study Results Further Validating Blood Tests for Alzheimer’s Disease

Foundation for the National Institutes of Health

The study compared the accuracy of leading commercial blood tests in detecting amyloid plaques, a characteristic feature of Alzheimer’s

Photo of researchers at a lab bench at the Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research Institute

Researchers Identify a New Genetic Form of Alzheimer's Disease

Sant Pau Research Institute

New findings suggest that having two copies of a specific gene could represent a new genetic form of Alzheimer's disease

Graphic illustration of a person holding their head with the brain and nerves are highlighted to indicate pain or headache.

FDA Approves Whole Blood Rapid Test for Assessing Brain Injury

U.S. Army Medical Materiel Development Activity

Traumatic brain injury is a major concern in the Army personnel and the new test could drive quick on-field diagnosis

A young boy in a wheelchair looks back into the camera.

FDA Approves First Nonsteroidal Drug for DMD

U.S. Food and Drug Administration

The FDA granted the approval of Duvyzat™ to Italfarmaco S.p.A

3D illustration of a nerve cell with myelinated axons and dendrites.

Gene Therapy Improves Rare Neurodegenerative Disease in Trial

National Institutes of Health

Treatment for giant axonal neuropathy was well tolerated and slowed loss of motor function

An elder woman in a wheelchair with Parkinson's smiles at a cheerful personal care worker who's crouching over the wheelchair, resting her hands on the elder woman.

Screening for Skin-Based Biomarker Helps Diagnose Parkinson’s

Beth Israel Deaconess Medical Center

Simple test detects the key biomarker in neurodegenerative diseases that could lead to earlier diagnosis and accelerate drug development

3D-rendered image of a human neuron network with myelin sheath on a black background.

FDA Approves First Gene Therapy for Metachromatic Leukodystrophy

U.S. Food and Drug Administration

The FDA granted approval of Lenmeldy™ to Orchard Therapeutics

A man having a headache touches his right temple as he sits wrapped in a duvet on a bed.

Treatments for Long COVID-Related Neurological Symptoms in Trials

National Institutes of Health

Trials will test at least three treatments for long COVID symptoms, such as fast heart rate, dizziness, and fatigue

A microscopic image of a lung cancer tissue biopsy showing stained tumor cells.

Novel Nanopipette Could Advance Single-Cell Analysis

University of Leeds

Learning how tumor cells adapt to treatment through nanobiopsy could aid in preventing cancer recurrence

A female clinician gestures as she explains the dosage and side effects of a medication to a worried young mother holding a baby.

Using Circulating mRNA in Blood as Brain Disorder Biomarkers

Johns Hopkins Medicine

Researchers used blood and organoids to study the role of mRNA carried by brain-specific EVs in PPD and psychiatric conditions

A 3D ribbon model of a protein molecule.

De novo Proteins in CSF Act as Brain Disorders Biomarkers

National Institutes of Health

Identifying and quantifying cryptic protein aggregates may help diagnose and develop therapies for brain disorders