Molecular Diagnostics Articles | Today's Clinical Lab

The future of STI diagnostics lies in combining molecular accuracy with operational simplicity.

Why STI Testing Still Isn’t Decentralized—Rethinking STI Diagnostics from Sample to Result

Siew Veena Sahi, MD

Bridging the diagnostic gap means tackling preanalytical challenges and designing workflows that go beyond instrument-centric approaches

The new technique could boost the accuracy of stool sample tests for IBD.

New Test Could Help Pinpoint IBD Diagnosis, Study Finds

University of Edinburgh

Researchers have developed a tool to measure the activity of a molecule linked to gut inflammation within fecal samples

Colorectal cancer is one of the most common cancers in the Western world.

DNA Testing of Colorectal Polyps Improves Insight into Hereditary Risks

Radboud University Medical Center

European collaboration demonstrates the value of targeted tumor analysis

Quagliata sat down with Today’s Clinical Lab at the Association for Molecular Pathology’s annual meeting in November.

Molecular Pathology Will Lean Further into Liquid Biopsy and Proteomics in 2026

Scott Wallask, BA, Luca Quagliata, PhD, BCMAS, COA

Thermo Fisher’s Luca Quagliata also discusses pathologists’ desire for rapid turnaround times

MOBILion’s strategy is to integrate its HRIM technology across the mass spectrometry ecosystem, extending beyond proteomics into metabolomics, lipidomics, exposomics, and other high-value analytical markets.

MOBILion Systems Reports Proof-of-Concept Data Supporting a New Proteomics Approach

MOBILion Systems, Inc.

Peer-reviewed and collaborator studies indicate high-resolution ion mobility may address longstanding ion utilization limits in LC-MS proteomics workflows

This approach could make detecting Alzheimer’s disease easier and less invasive.

Dried Blood Spot Testing Shows Early Promise for Alzheimer’s Biomarkers

Springer Nature

Researchers report that dried blood spots can reliably measure p-tau217 and other Alzheimer’s biomarkers in a controlled research setting

As 2026 approaches, clinical labs and biopharma are entering a period of rapid innovation.

7 Emerging Trends Shaping Clinical Labs in 2026

Today's Clinical Lab

Expert perspectives on how AI, data governance, genomics, patient-centric care, and other emerging trends are shaping the future of clinical labs

Bladder cancer is among the most common and most expensive cancers to monitor, with an estimated 83,190 new US cases in 2024 and 800,000 living with the disease nationwide.

Cellens Secures $6.5M to Advance AI and Mechanobiology-Based Bladder Cancer Test

Cellens

The test leverages cellular biophysics and machine learning to offer a high-sensitivity alternative to traditional urine-based assays

Instead of relying solely on clinical endpoints over extended treatment periods, the research examined whether molecular signals could reveal pharmacodynamic activity within the first few days of treatment.

Rapid Transcriptomics Brings Actionable Data to Early-Phase Topical Trials

Stéphanie Légaré, PhD

Early transcriptomic readouts reveal pharmacodynamic activity in skin within days—a shift toward earlier molecular decision-making

The researchers are validating the model as a clinical test.

A New Way to Diagnose Deadly Lung Infections and Save Lives

University of California - San Francisco

Researchers at UC San Francisco have devised a method to identify pneumonia—using both genetic information and AI—that could curb the overuse of antibiotics

The study confirms previous preliminary results by comparing four biomarkers using an analysis method that can be applied in clinical settings.

Blood Test Reveals Prognosis After Cardiac Arrest

Lund University

Researchers compared four blood-based brain injury biomarkers across multiple centers to evaluate how reliably they estimate the extent of brain damage in unconscious patients after cardiac arrest

If even 1 percent of adults in the US became kidney or partial liver living donors, the waitlists for kidney and liver transplants would significantly decrease.

Enhancing Transplant Success with Living Organ Donation and Advanced Diagnostics

Tina Liedtky

As demand for organs grows, laboratory diagnostics remain central to donor evaluation and transplant success

STIs remain a largely silent epidemic, with 80 percent of chlamydia and gonorrhea infections going undiagnosed each year.

Collaboration Tackles Critical Gaps in US STI Diagnostics

Testmate Health, Intermountain Health

Intermountain Health’s support accelerates Testmate’s deployment of rapid molecular tests where patients often face delayed results or no access to lab-quality testing

Today’s Clinical Lab 2026 All-Inclusive Pass: Your Single Access Point for the Year

Today's Clinical Lab

Sign up for all our 2026 digital forums with one click

Researchers are now targeting clonal hematopoiesis and building new solutions to help make liquid biopsy a frontline defense in the fight against cancer.

Beyond the Blood Draw: Making Liquid Biopsy More Accurate, One Mutation at a Time

Matthew Oberley, MD, PhD

As liquid biopsy becomes a standard tool in oncology, distinguishing tumor signals from clonal hematopoiesis is essential for accurate results

Extracellular vesicles are nanometer-sized particles shed into body fluids, including blood and urine, that carry molecular information relevant to understanding, diagnosing, and treating cancer, degenerative diseases, and conditions in regenerative medicine.

Seed Funding Drives Development of Benchtop Exosome System for Precision Medicine

Hermes Biosciences

Hands-off isolation technology delivers higher yield and quality of extracellular vesicles, enabling reproducible workflows for clinical research and diagnostics