Toward a Faster and More Accurate Psoriatic Arthritis Diagnosis
Tiffany Payne, MS
Experts discuss key challenges and advancements in diagnosing psoriatic arthritis and the importance of early diagnosis
Immunology
Navigating Celiac Disease Testing
Tyler Radke, MLS(ASCP)CM
A working knowledge of celiac disease testing options increases effectiveness of detection and diagnosis
A Clinical Lab Manager’s Guide to Antimicrobial Stewardship
Today's Clinical Lab
Explore the latest strategies and essential elements for effective antimicrobial stewardship in health care settings
World-First Home Oral Glucose Tolerance Testing (OGTT) Technology for Gestational Diabetes Screening
Digostics
Medway NHS Foundation Trust to transform local gestational diabetes screening by improving access to a new at-home diabetes testing technology
Distinct T-cell Signatures Observed at Different Stages of Type 1 Diabetes Development
University of Eastern Finland
Two distinct signatures were detected in a subset of circulating, highly differentiated CD8-positive T cells in children at different stages of T1D
The Nuances of Antinuclear Antibodies Testing in Rheumatologic Diseases
Tyler Radke, MLS(ASCP)CM, Kali Vincent, MLS(ASCP)CM
Strong working knowledge of ANA testing in rheumatologic diseases increases effectiveness of detection and diagnosis
Testing Immune Cells in the Placenta May Indicate the Health of Fetal Brain Immune Cells
Massachusetts General Hospital
Assessing these placental cells may reveal when immune activation in a pregnant woman negatively affects the development of fetal brain immune cells
Gene Variants Increase the Risk for Persistent HPV Infections
University of Maryland School of Medicine
First genome-wide association study finds variants linked to susceptibility of cervical cancer-causing virus
FDA Approves New Antibiotic for Multiple Bacterial Infections
U.S. Food and Drug Administration
The FDA granted the approval of Zevtera® to Basilea Pharmaceutica International Ltd.
A Simple Blood Test Could Detect TB in Asymptomatic Patients
University of Southampton
Tuberculosis is the world's deadliest infectious disease and kills more than 1 million people each year, per the WHO
PARP Inhibitor Delays Uterine Cancer Recurrence in Phase 2 Trial
University of Colorado Anschutz Medical Campus
There are currently no approved maintenance therapies for metastatic and recurrent uterine/endometrial cancer
Postsurgery Immunotherapy Doesn’t Improve Survival in Breast Cancer
European Organisation for Research and Treatment of Cancer
Adding atezolizumab immunotherapy to postsurgery chemotherapy doesn’t have the same benefits as the pre-surgery regimen
FDA Approves First Gene Therapy for Metachromatic Leukodystrophy
U.S. Food and Drug Administration
The FDA granted approval of Lenmeldy™ to Orchard Therapeutics
New ML Model Identifies Tumor-Reactive T Cells Quickly
German Cancer Research Center (Deutsches Krebsforschungszentrum)
icTCR helps identify suitable T cells from patient samples in under a few days, not months
Monocyte Count Predicts Lung Disease Risk in COVID-19 Patients
University of Virginia Health System
A simple blood test result can inform clinicians which patients with severe COVID-19 will develop long-haul lung problems
Mycobacteria Present in Symptomatic Patients with Suspected TB
Amsterdam University Medical Centers
Study shows that Mtb is present in the exhaled breath of 90 percent of people suspected to have TB, despite their negative sputum tests
Nirsevimab Effectively Protects Infants from RSV
Centers for Disease Control and Prevention
The CDC data show nirsevimab is 90 percent effective in preventing infants from being hospitalized with RSV
A New Take on Antenatal Immunohematology Testing
Arnaud Reggiani, Biol. Eng., MSc
Automating antenatal antibody testing can help save time and resources and reduce the burden on skilled lab personnel
IL-13Rα2-Targeting CAR T-Cell Therapy Improves Brain Cancer
City of Hope
Researchers were able to deliver the CAR-T cells directly into the tumor site and the cerebrospinal fluid
mAb Combo Therapy Safe to Treat Advanced Cancers
Wiley
CS1002 plus CS1003 showed promising antitumor activity and had a manageable safety profile across a broad dosing range in trials