Immunology Articles | Today's Clinical Lab

Photo of a woman holding a blue surgical mask up to her face.

Immune Responses to SARS-CoV-2 Changed After Omicron, Study Shows

Springer Nature

New findings show the protective effects of natural infection against SARS-CoV-2 reduced substantially in the post-Omicron era

Of the many genes involved in rheumatoid arthritis and osteoporosis, the researchers identified two key genes, ATXN2L and MMP14, that are most strongly linked to both diseases.

Two Key Genes Identified Linking Rheumatoid Arthritis and Osteoporosis

American Institute of Physics

The genes, involved in both diseases, could serve as targets for diagnosis and treatment

Photo of a white N95 face mask with yellow straps against a white background.

Repeated COVID-19 Vaccines Enhance Mucosal Immunity Against the Virus

Vlaams Instituut voor Biotechnologie

New findings suggest that repeated COVID-19 vaccinations not only bolster systemic immunity but also enhance mucosal antibody responses

Maximize Lab Operations with an Efficient Water Purification System

MilliporeSigma

Improve patient care with laboratory water systems–reducing maintenance burdens, and ensuring reliable test results

Photo of a blood test tube with a yellow cap next to a testing requisition for ANA testing for autoimmune disease.

Toward a Faster and More Accurate Psoriatic Arthritis Diagnosis

Tiffany Payne, MS

Experts discuss key challenges and advancements in diagnosing psoriatic arthritis and the importance of early diagnosis

Illustration of a wheat plant overlapped with a stop sign representing wheat sensitivity in celiac disease on a green background.

Navigating Celiac Disease Testing

Tyler Radke, MLS(ASCP)CM

A working knowledge of celiac disease testing options increases effectiveness of detection and diagnosis

A Clinical Lab Manager’s Guide to Antimicrobial Stewardship

Biomerieux

Explore the latest strategies and essential elements for effective antimicrobial stewardship in health care settings

World-First Home Oral Glucose Tolerance Testing (OGTT) Technology for Gestational Diabetes Screening

Digostics

Medway NHS Foundation Trust to transform local gestational diabetes screening by improving access to a new at-home diabetes testing technology

Photo of a clinical laboratory scientist wearing PPE and performing a flow cytometry analysis on T cells in diabetes samples.

Distinct T-cell Signatures Observed at Different Stages of Type 1 Diabetes Development

University of Eastern Finland

Two distinct signatures were detected in a subset of circulating, highly differentiated CD8-positive T cells in children at different stages of T1D

Photo of a blood sample in a test tube for ANA testing in clinical laboratory.

The Nuances of Antinuclear Antibodies Testing in Rheumatologic Diseases

Tyler Radke, MLS(ASCP)CM, Kali Vincent, MLS(ASCP)CM

Strong working knowledge of ANA testing in rheumatologic diseases increases effectiveness of detection and diagnosis

Illustration of transparent human placenta cells floating on an orange background.

Testing Immune Cells in the Placenta May Indicate the Health of Fetal Brain Immune Cells

Massachusetts General Hospital

Assessing these placental cells may reveal when immune activation in a pregnant woman negatively affects the development of fetal brain immune cells

3D rendering of human papillomavirus, one of the most common oncogenic viruses and causes cervical cancer.

Gene Variants Increase the Risk for Persistent HPV Infections

University of Maryland School of Medicine

First genome-wide association study finds variants linked to susceptibility of cervical cancer-causing virus

A vector illustration of a male researcher holding a magnifying lens at a capsule as drugs of various sizes and shapes are lined up on a belt on either side.

FDA Approves New Antibiotic for Multiple Bacterial Infections

U.S. Food and Drug Administration

The FDA granted the approval of Zevtera® to Basilea Pharmaceutica International Ltd.

Vacutainers filled with collected blood samples are ready to be analyzed.

A Simple Blood Test Could Detect TB in Asymptomatic Patients

University of Southampton

Tuberculosis is the world's deadliest infectious disease and kills more than 1 million people each year, per the WHO

A clinician with gloved hands points with a pen to a model of the female reproductive system with tumors in the uterine wall.

PARP Inhibitor Delays Uterine Cancer Recurrence in Phase 2 Trial

University of Colorado Anschutz Medical Campus

There are currently no approved maintenance therapies for metastatic and recurrent uterine/endometrial cancer

A multiethnic group of five women of mixed ages stand together outdoors, each holding a breast cancer awareness ribbon near the camera.

Postsurgery Immunotherapy Doesn’t Improve Survival in Breast Cancer

European Organisation for Research and Treatment of Cancer

Adding atezolizumab immunotherapy to postsurgery chemotherapy doesn’t have the same benefits as the pre-surgery regimen

3D-rendered image of a human neuron network with myelin sheath on a black background.

FDA Approves First Gene Therapy for Metachromatic Leukodystrophy

U.S. Food and Drug Administration

The FDA granted approval of Lenmeldy™ to Orchard Therapeutics

A graphical illustration of a clinician pointing to a vector of a human body, vaccine, stethoscope, brain, lungs, kidneys, and heart.

New ML Model Identifies Tumor-Reactive T Cells Quickly

German Cancer Research Center (Deutsches Krebsforschungszentrum)

icTCR helps identify suitable T cells from patient samples in under a few days, not months

Three yet-to-be-labeled blood vacutainers are placed on a test order form with a stethoscope on the side.

Monocyte Count Predicts Lung Disease Risk in COVID-19 Patients

University of Virginia Health System

A simple blood test result can inform clinicians which patients with severe COVID-19 will develop long-haul lung problems

A woman sitting at her desk with laptop, phone, etc., rubs her nose with her right and touches her throat with her left hand to indicate infection.

Mycobacteria Present in Symptomatic Patients with Suspected TB

Amsterdam University Medical Centers

Study shows that Mtb is present in the exhaled breath of 90 percent of people suspected to have TB, despite their negative sputum tests