Genetics Articles | Today's Clinical Lab

Photo of two fingers turning a dice, which changes the word from "negative" to "positive.”

Scientists Uncover How Retinoic Acid ‘Treats’ Neuroblastoma

Today's Clinical Lab

Researchers reveal how retinoic acid works against metastatic neuroblastoma, offering new insights into its role in treatment and paving the way for future therapies

Illustration of cancer cells releasing circulating tumor DNA (ctDNA), which can be analyzed via blood-based genetic testing to identify mutations in childhood cancers.

UK’s Precision Medicine Program Uses Blood Tests to Advance Childhood Cancer Treatments

Today's Clinical Lab

The first phase of the Stratified Medicine Paediatrics program shows that ctDNA blood tests can provide crucial insights for targeting treatments and tracking childhood cancer progression

No Cold Storage, No Hassle—Precision PCR with Lyophilized Beads

Promega

Improve accuracy, reduce contamination, and keep up with high-throughput demands using room-temperature stable PCR reagents

Illustration of a double helix representing genetic material against a blue background.

AlidaBio Launches EpiPlex™ Platform to Advance Epitranscriptomic Research

AlidaBio

EpiPlex is first platform to offer multitarget, quantitative analysis of RNA modifications to provide comprehensive detection and characterization of the epitranscriptome

Photo of bench top analyzers used to test genetic material in a clinical laboratory.

Study Shows Urine Test for Prostate Cancer Could Be Used at Home

Vanderbilt University Medical Center

The test could enable at-home testing and increased access to testing for patients undergoing telehealth care or living in remote areas

Photo of many patient files representing the thousands of participants enrolled in a study.

GUARDIAN Study: Genomic Newborn Screening Will Transform the Rare Disease Landscape

Paul Kruszka, MD, MPH, FACMG

The GUARDIAN offers proof of principle that we can implement advanced genomic testing on a large scale

OGT’s next-generation sequencing SureSeq™ Myeloid MRD Panel, which provides a flexible NGS workflow.

OGT delivers superior MRD detection capabilities with new SureSeq Myeloid MRD Panel

OGT

Ultralow variant detection enables a stronger characterization of a sample’s current AML status

Illustration of clinical laboratory professionals wearing lab coats with DNA molecules in the background to represent Sanger sequencing

Sanger Sequencing for Specific and Small-Scale DNA Testing

Zahraa Chorghay, PhD

Cost, time, and labor considerations still make the Sanger method a better choice amidst new sequencing technologies

Illustration of colorful DNA helices representing genetic testing against a yellow background.

New NCCN Patient Resource Shares Latest Understanding of Genetic Testing to Guide Patient Decision Making

National Comprehensive Cancer Network

New resource from the National Comprehensive Cancer Network outlines how and why to access genetic counseling and testing for multiple hereditary cancers

Illustration of a network of human brain neurons sending out electrical signals.

Study Reveals 2 New Genes Associated with Variants Linked to Epilepsy, Offering New Hope for Personalized Therapies

University of Texas Health Science Center at Houston

By linking epilepsy to specific genetic mutations, the research offers a new framework for understanding the disorder and developing therapies that address its root causes

New England Biolabs Launches EM-seq v2, an Updated Kit for More Sensitive Detection of 5mC and 5hmC

New England Biolabs

This bisulfite-free method of methylation detection provides a faster, more streamlined workflow that enables highly sensitive analysis

Photo of a clinical lab professional wearing a white lab coat and gloves loading blood samples from myelodysplastic syndrome patients for lab testing.

ASH 2024: Study Shows Genetic Mutations Accumulate in Smokers with Myelodysplastic Syndromes and Worsen Outcomes

University of Miami Miller School of Medicine

Study is the first to identify discrete genetic mutations associated with smoking, to establish a dose-response relationship between smoking and genetic mutations and to show that continuing to smoke leads to more mutations and worse MDS

Illustration of vertical line drawing representing the DNA molecular helix in dark pink against a light pink background.

New CRISPR Toolkit to Allow Remote-Controlled Genome Editing

University of Southern California

USC Viterbi biomedical engineers harness focused ultrasound to revolutionize CRISPR’s capabilities to treat countless diseases

Photo of Dr. Manuel Irimia, coordinator of EvoMG.

Barcelona Launches World’s First Evolutionary Medical Genomics Program

Centre for Genomic Regulation

CRG, UPF, and IBE researchers are teaming up to explore the evolutionary underpinnings of disease at the molecular level

Illustration of a DNA double helix symbol in the middle of the image with many 3D hexagons with the sequencing letters ATGC representing the concept of genomics sequencing testing in a clinical laboratory.

Azenta Obtains Regulatory Approval for Clinical Long-Read Whole Genome Sequencing Test

Azenta

The test enables precise detection of a range of complex genomic alterations that are features of many rare diseases and undetectable by traditional approaches