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Emerging Diagnostic Modalities & Innovation

The kit is intended to support research workflows that seek to better understand the biological mechanisms underlying disease by connecting genetic variation, gene expression, and protein-level activity.
|2 min read

Thermo Fisher Launches All-in-One Kit for Sequential DNA, RNA and Protein Extraction

Integrated solution simplifies multi-layer molecular analysis, advancing precision medicine and translational research
byThermo Fisher Scientific
Tumors are composed of different cancer cells that vary in their aggressiveness and sensitivity to treatments, and further research is needed to understand how liquid biopsies can capture this diversity.
|2 min read

DNA Barcoding Reveals the Complexity of Breast Cancer Liquid Biopsies

Optimized DNA barcoding showed that similar-looking tumors can release different amounts of DNA into the bloodstream
byOlivia Newton-John Cancer Research Institute
Once largely confined to oncology, CDx is rapidly becoming a foundational pillar of precision medicine, enabling clinicians to match the right therapy with the right patient at the right time.
|3 min read

The Future of Companion Diagnostics: A Multi-Omics Revolution

The landscape of companion diagnostics is poised for transformative growth, driven by technological innovation, expanding therapeutic applications, and evolving regulatory support
byMadhuri Hegde, PhD, FACMG
The pilot program marks a dramatic change.
|5 min read

Medicare Is Experimenting with Having AI Review Claims—a Cost-Saving Measure That Could Risk Denying Needed Care

A new pilot brings some automated treatment decisions from Medicare Advantage to traditional Medicare
byGrace Mackleby, PhD andJeff Marr, PhD
Under the redlining policy, federal agencies and banks created maps that designated neighborhoods as A (“best”) to D (“hazardous,” colored red on maps) for mortgage lending based on race, ethnicity, and class.
|2 min read

Have Associations Between Historical Redlining and Breast Cancer Survival Changed Over Time?

Study finds that disparities generally narrowed from 1995–2014, but subsequently widened
byWiley
Despite ongoing efforts to improve it, around 90 percent of clinical drug development still fails.
|3 min read

Regulating the Future: How the FDA Is Defining the Role of AI in Clinical Development

The FDA is embracing a data-driven, patient-centered approach to clinical trials
byGen Li, PhD, MBA
One of the most widely recognized issues is that AI models can replicate societal biases and systematically underestimate risk or misclassify disease in historically marginalized populations.
|2 min read

ADLM Advocates for the Federal Government to Support Equitable Healthcare AI

The statement calls on Congress and federal agencies to modernize existing laboratory regulations and to implement policies to ensure that AI clinical systems are safe and effective
byAssociation for Diagnostics and Laboratory Medicine
The researchers used retrospective clinical data from 113 patients treated for prostate cancer at University of California Los Angeles (UCLA) Jonsson Comprehensive Cancer Center.
|2 min read

New Study Unlocks Important Information About How to Treat Recurring Prostate Cancer

Routine PSMA PET/CT scans could help doctors select the best treatments for long-term outcomes in patients with recurring prostate cancer after surgical removal of the prostate
byNational Comprehensive Cancer Network
Interpretation of lymph node histology is quite complex, with significant inter-observer variability, further complicating diagnosis and blurring prognostic clarity.
|3 min read

Improving the Diagnosis and Assessment of Castleman Disease

New efforts aim to overcome diagnostic and histologic challenges in Castleman disease
byAlessandro Albuquerque, MD, MSc, PhD
Cancer cells (red) stick to mesothelial cells (green) and form hybrid spheres that cut into surrounding abdominal tissue.
|2 min read

Why Ovarian Cancer Spreads So Rapidly in the Abdomen

Study finds floating ovarian cancer cells recruit mesothelial cells in abdominal fluid to create cancer clusters
byNagoya City University
While AI and automation bring efficiencies, they are not a substitute for human expertise.
|2 min read

Transforming Clinical Lab Workflows with AI and Automation

Laboratories that embrace these innovations today will be better positioned to meet tomorrow’s challenges
byRyan Thompson
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Ensuring Compliance: How to Get AI Diagnostic Tools Approved for Clinical Practice

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