Clinical Focus

Labcorp MRD tests now monitor recurrence risk across stage I–III breast cancer, stage I–IIIA non-small cell lung cancer and stage III colon cancer

The research could help develop representative biomarkers and treatment strategies—bringing more precise and effective health care to millions of people

UC engineers introduce PanMAN, a data structure that compresses and encodes large-scale genomic variation and evolutionary history, transforming microbial and human genome studies

Bridging the diagnostic gap means tackling preanalytical challenges and designing workflows that go beyond instrument-centric approaches

Exactly how Epstein-Barr virus contributes to MS has long been unclear

Researchers have developed a tool to measure the activity of a molecule linked to gut inflammation within fecal samples

Researchers have shown that a blood test that can predict Crohn’s disease years before symptoms appear, opening the doors to early diagnosis and potentially prevention

European collaboration demonstrates the value of targeted tumor analysis

Thermo Fisher’s Luca Quagliata also discusses pathologists’ desire for rapid turnaround times

Peer-reviewed and collaborator studies indicate high-resolution ion mobility may address longstanding ion utilization limits in LC-MS proteomics workflows

Researchers report that dried blood spots can reliably measure p-tau217 and other Alzheimer’s biomarkers in a controlled research setting

Researchers present an innovative computational method based on modern mathematics to shed light on cell state dynamics and development

In Science’s first editorial of 2026, editor-in-chief Holden Thorp reflects on thoughtful AI use in scientific publishing

Five experts at Thermo Fisher Scientific share their perspectives on technology, workforce, and operational shifts shaping the future of the clinical lab

OHSU researchers identified new drug combination that could overcome treatment resistance in acute myeloid leukemia

Study of 12.6 million births shows 36 percent jump in gestational diabetes during the past decade

Expert perspectives on how AI, data governance, genomics, patient-centric care, and other emerging trends are shaping the future of clinical labs

The test leverages cellular biophysics and machine learning to offer a high-sensitivity alternative to traditional urine-based assays

Researchers found that switching from paper to electronic medical records at HIV clinics in Malawi led to an estimated 28 percent reduction in deaths after five years

From regulatory shifts to breakthrough diagnostics, the stories that defined clinical labs in 2025