Articles by Baylor College of Medicine

New findings show that specific p53 variants, such as R273H, may predict stronger responses to immune checkpoint inhibitors

The findings support further clinical studies to determine whether this marker may help identify patients who could benefit from CDK4/6 inhibitors

Combining clinical lab expertise with highly curated datasets and automated technology has provided new insights for the most complex genetic conditions

Blocking proteins that activate the AGC group of enzymes has been shown to have tumor-suppressing effects

Identifying the right set of patients using a molecular test can help effectively deliver a personalized, chemotherapy-free treatment regimen

Trial validates localization of NKT cells to tumor sites in humans and points to high in vivo antitumor activity

Proteins and small molecules involved in DNA repair play a key role in creating bacterial mutants with antibiotic resistance

A computer analysis pipeline that helps detect contaminants in samples that contain little microbial DNA

These cancers are less likely to respond to chemotherapy and patient outcomes are poor

Identifying rare variant risk factors in individuals with schizophrenia could lead to better understanding of prognosis

Method known as untargeted metabolomics profiling can improve the diagnostic rate for rare genetic conditions

The analyses revealed new therapeutics targets in different subtypes of breast cancer, a step toward personalized cancer care

Study finds that beginning with RNA sequencing could increase diagnostic yield by 17 percent

Researchers have been working on improving their ability to identify the genetic cause of undiagnosed conditions

A particular combination of two maternal and one fetal gene variants seems to predispose women to preeclampsia